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The high infectivity of SARS-CoV-2 B.1.1.7 is associated with increased interaction force between Spike-ACE2 caused by the viral N501Y mutation

View ORCID ProfileJadson C. Santos, View ORCID ProfileGeraldo A. Passos
doi: https://doi.org/10.1101/2020.12.29.424708
Jadson C. Santos
1Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto Campus, SP, Brazil
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Geraldo A. Passos
1Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto Campus, SP, Brazil
2Laboratory of Genetics and Molecular Biology, Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto Campus, SP, Brazil
3Center for Cell-Based Therapy in Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto Campus, SP, Brazil
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  • For correspondence: passos@usp.br
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Article Information

doi 
https://doi.org/10.1101/2020.12.29.424708
History 
  • January 1, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Jadson C. Santos1 and
  2. Geraldo A. Passos1,2,3,*
  1. 1Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto Campus, SP, Brazil
  2. 2Laboratory of Genetics and Molecular Biology, Department of Basic and Oral Biology, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto Campus, SP, Brazil
  3. 3Center for Cell-Based Therapy in Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto Campus, SP, Brazil
  1. ↵*Correspondent author at: Molecular Immunogenetics Group, Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto Campus, SP, Brazil. E-mail: passos{at}usp.br
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Posted January 01, 2021.
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The high infectivity of SARS-CoV-2 B.1.1.7 is associated with increased interaction force between Spike-ACE2 caused by the viral N501Y mutation
Jadson C. Santos, Geraldo A. Passos
bioRxiv 2020.12.29.424708; doi: https://doi.org/10.1101/2020.12.29.424708
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The high infectivity of SARS-CoV-2 B.1.1.7 is associated with increased interaction force between Spike-ACE2 caused by the viral N501Y mutation
Jadson C. Santos, Geraldo A. Passos
bioRxiv 2020.12.29.424708; doi: https://doi.org/10.1101/2020.12.29.424708

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