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Proton-gated coincidence detection is a common feature of GPCR signaling

View ORCID ProfileNicholas J. Kapolka, View ORCID ProfileJacob B. Rowe, View ORCID ProfileGeoffrey J. Taghon, View ORCID ProfileWilliam M. Morgan, Corin R. O’Shea, View ORCID ProfileDaniel G. Isom
doi: https://doi.org/10.1101/2021.01.08.425945
Nicholas J. Kapolka
aDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136
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Jacob B. Rowe
aDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136
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Geoffrey J. Taghon
aDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136
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William M. Morgan
aDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136
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Corin R. O’Shea
aDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136
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Daniel G. Isom
aDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136
bUniversity of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136
cUniversity of Miami Institute for Data Science and Computing, Miami, FL 33146
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  • For correspondence: disom@miami.edu
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Article Information

doi 
https://doi.org/10.1101/2021.01.08.425945
History 
  • January 9, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Nicholas J. Kapolkaa,
  2. Jacob B. Rowea,
  3. Geoffrey J. Taghona,
  4. William M. Morgana,
  5. Corin R. O’Sheaa and
  6. Daniel G. Isoma,b,c,*
  1. aDepartment of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL 33136
  2. bUniversity of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136
  3. cUniversity of Miami Institute for Data Science and Computing, Miami, FL 33146
  1. ↵*Corresponding author: Daniel G. Isom: disom{at}miami.edu
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Posted January 09, 2021.
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Proton-gated coincidence detection is a common feature of GPCR signaling
Nicholas J. Kapolka, Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea, Daniel G. Isom
bioRxiv 2021.01.08.425945; doi: https://doi.org/10.1101/2021.01.08.425945
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Proton-gated coincidence detection is a common feature of GPCR signaling
Nicholas J. Kapolka, Jacob B. Rowe, Geoffrey J. Taghon, William M. Morgan, Corin R. O’Shea, Daniel G. Isom
bioRxiv 2021.01.08.425945; doi: https://doi.org/10.1101/2021.01.08.425945

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