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Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate
View ORCID ProfileEndika Prieto-Fernández, View ORCID ProfileLeire Egia-Mendikute, View ORCID ProfileLaura Vila-Vecilla, View ORCID ProfileAlexandre Bosch, View ORCID ProfileAdrián Barreira-Manrique, So Young Lee, View ORCID ProfileAna García-del Río, View ORCID ProfileAsier Antoñana-Vildosola, Borja Jiménez-Lasheras, Leire Moreno-Cugnon, Jesús Jiménez-Barbero, Edurne Berra, June Ereño-Orbea, View ORCID ProfileAsis Palazon
doi: https://doi.org/10.1101/2021.01.09.426021
Endika Prieto-Fernández
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Leire Egia-Mendikute
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Laura Vila-Vecilla
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Alexandre Bosch
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Adrián Barreira-Manrique
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
So Young Lee
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Ana García-del Río
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Asier Antoñana-Vildosola
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Borja Jiménez-Lasheras
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Leire Moreno-Cugnon
2Cancer Cell Signaling and Metabolism Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
Jesús Jiménez-Barbero
3Chemical Glycobiology Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
4Department of Organic Chemistry II, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Spain
5Ikerbasque, Basque Foundation for Science, Bilbao, Spain
Edurne Berra
2Cancer Cell Signaling and Metabolism Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
6CIBERONC (Centro de Investigación Biomédica en Red de Cáncer), Madrid, Spain
June Ereño-Orbea
3Chemical Glycobiology Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
5Ikerbasque, Basque Foundation for Science, Bilbao, Spain
Asis Palazon
1Cancer Immunology and Immunotherapy Lab, Centre for Cooperative Research in Biosciences (CIC bioGUNE), Basque Research and Technology Alliance (BRTA), Bizkaia Technology Park, Building 801A, Derio, Spain
5Ikerbasque, Basque Foundation for Science, Bilbao, Spain
Article usage
Posted May 17, 2021.
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate
Endika Prieto-Fernández, Leire Egia-Mendikute, Laura Vila-Vecilla, Alexandre Bosch, Adrián Barreira-Manrique, So Young Lee, Ana García-del Río, Asier Antoñana-Vildosola, Borja Jiménez-Lasheras, Leire Moreno-Cugnon, Jesús Jiménez-Barbero, Edurne Berra, June Ereño-Orbea, Asis Palazon
bioRxiv 2021.01.09.426021; doi: https://doi.org/10.1101/2021.01.09.426021
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate
Endika Prieto-Fernández, Leire Egia-Mendikute, Laura Vila-Vecilla, Alexandre Bosch, Adrián Barreira-Manrique, So Young Lee, Ana García-del Río, Asier Antoñana-Vildosola, Borja Jiménez-Lasheras, Leire Moreno-Cugnon, Jesús Jiménez-Barbero, Edurne Berra, June Ereño-Orbea, Asis Palazon
bioRxiv 2021.01.09.426021; doi: https://doi.org/10.1101/2021.01.09.426021
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