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GeneFriends 2021: Updated co-expression databases and tools for human and mouse genes and transcripts

Priyanka Raina, Inês Lopes, Kasit Chatsirisupachai, Zoya Farooq, View ORCID ProfileJoão Pedro de Magalhães
doi: https://doi.org/10.1101/2021.01.10.426125
Priyanka Raina
1Integrative Genomics of Ageing Group, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK
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Inês Lopes
1Integrative Genomics of Ageing Group, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK
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Kasit Chatsirisupachai
1Integrative Genomics of Ageing Group, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK
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Zoya Farooq
1Integrative Genomics of Ageing Group, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK
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João Pedro de Magalhães
1Integrative Genomics of Ageing Group, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK
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  • ORCID record for João Pedro de Magalhães
  • For correspondence: jp@senescence.info
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ABSTRACT

Gene co-expression analysis has emerged as a powerful method to provide insights into gene function and regulation. The rapid growth of publicly available RNA-sequencing (RNA-seq) data has created opportunities for researchers to employ this abundant data to help decipher the complexity and biology of genomes. Co-expression networks have proven effective for inferring relationship between the genes, for gene prioritization and for assigning function to poorly annotated genes based on their co-expressed partners. To facilitate such analyses we created previously an online co-expression tool for humans and mice entitled GeneFriends. To continue providing a valuable tool to the scientific community, we have updated the GeneFriends database. Here, we present the latest version of GeneFriends, which includes updated gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples. GeneFriends is freely available at http://www.genefriends.org/

Competing Interest Statement

The authors have declared no competing interest.

Footnotes

  • http://www.genefriends.org/

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
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Posted January 10, 2021.
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GeneFriends 2021: Updated co-expression databases and tools for human and mouse genes and transcripts
Priyanka Raina, Inês Lopes, Kasit Chatsirisupachai, Zoya Farooq, João Pedro de Magalhães
bioRxiv 2021.01.10.426125; doi: https://doi.org/10.1101/2021.01.10.426125
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GeneFriends 2021: Updated co-expression databases and tools for human and mouse genes and transcripts
Priyanka Raina, Inês Lopes, Kasit Chatsirisupachai, Zoya Farooq, João Pedro de Magalhães
bioRxiv 2021.01.10.426125; doi: https://doi.org/10.1101/2021.01.10.426125

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