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Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment

View ORCID ProfileMary Hongying Cheng, View ORCID ProfileJames M Krieger, View ORCID ProfileBurak Kaynak, View ORCID ProfileMoshe Arditi, View ORCID ProfileIvet Bahar
doi: https://doi.org/10.1101/2021.01.10.426143
Mary Hongying Cheng
1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
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James M Krieger
1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
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Burak Kaynak
1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
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Moshe Arditi
2Department of Pediatrics, Division of Pediatric Infectious Diseases and Immunology, and Biomedical Sciences, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
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Ivet Bahar
1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
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  • For correspondence: bahar@pitt.edu
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Article Information

doi 
https://doi.org/10.1101/2021.01.10.426143
History 
  • January 11, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Mary Hongying Cheng1,
  2. James M Krieger1,
  3. Burak Kaynak1,
  4. Moshe Arditi2 and
  5. Ivet Bahar1,*
  1. 1Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
  2. 2Department of Pediatrics, Division of Pediatric Infectious Diseases and Immunology, and Biomedical Sciences, Infectious and Immunologic Diseases Research Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
  1. ↵*To whom correspondence should be addressed. bahar{at}pitt.edu
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Posted January 11, 2021.
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Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment
Mary Hongying Cheng, James M Krieger, Burak Kaynak, Moshe Arditi, Ivet Bahar
bioRxiv 2021.01.10.426143; doi: https://doi.org/10.1101/2021.01.10.426143
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Impact of South African 501.V2 Variant on SARS-CoV-2 Spike Infectivity and Neutralization: A Structure-based Computational Assessment
Mary Hongying Cheng, James M Krieger, Burak Kaynak, Moshe Arditi, Ivet Bahar
bioRxiv 2021.01.10.426143; doi: https://doi.org/10.1101/2021.01.10.426143

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