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SARS-CoV-2 spike protein arrested in the closed state induces potent neutralizing responses
View ORCID ProfileGeorge W. Carnell, View ORCID ProfileKatarzyna A. Ciazynska, View ORCID ProfileDavid A. Wells, Xiaoli Xiong, Ernest T. Aguinam, View ORCID ProfileStephen H. McLaughlin, Donna Mallery, Soraya Ebrahimi, Lourdes Ceron-Gutierrez, View ORCID ProfileLeo C. James, Rainer Doffinger, View ORCID ProfileJonathan L. Heeney, View ORCID ProfileJohn A. G. Briggs
doi: https://doi.org/10.1101/2021.01.14.426695
George W. Carnell
1Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
Katarzyna A. Ciazynska
2Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
David A. Wells
3DIOSynVax, University of Cambridge, Cambridge, United Kingdom
Xiaoli Xiong
2Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
Ernest T. Aguinam
1Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
Stephen H. McLaughlin
2Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
Donna Mallery
2Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
Soraya Ebrahimi
4Department of Clinical Biochemistry and Immunology, Addenbrooke’s Hospital, Cambridge, United Kingdom
Lourdes Ceron-Gutierrez
4Department of Clinical Biochemistry and Immunology, Addenbrooke’s Hospital, Cambridge, United Kingdom
Leo C. James
2Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
Rainer Doffinger
4Department of Clinical Biochemistry and Immunology, Addenbrooke’s Hospital, Cambridge, United Kingdom
Jonathan L. Heeney
1Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
3DIOSynVax, University of Cambridge, Cambridge, United Kingdom
John A. G. Briggs
2Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
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Posted January 14, 2021.
SARS-CoV-2 spike protein arrested in the closed state induces potent neutralizing responses
George W. Carnell, Katarzyna A. Ciazynska, David A. Wells, Xiaoli Xiong, Ernest T. Aguinam, Stephen H. McLaughlin, Donna Mallery, Soraya Ebrahimi, Lourdes Ceron-Gutierrez, Leo C. James, Rainer Doffinger, Jonathan L. Heeney, John A. G. Briggs
bioRxiv 2021.01.14.426695; doi: https://doi.org/10.1101/2021.01.14.426695
SARS-CoV-2 spike protein arrested in the closed state induces potent neutralizing responses
George W. Carnell, Katarzyna A. Ciazynska, David A. Wells, Xiaoli Xiong, Ernest T. Aguinam, Stephen H. McLaughlin, Donna Mallery, Soraya Ebrahimi, Lourdes Ceron-Gutierrez, Leo C. James, Rainer Doffinger, Jonathan L. Heeney, John A. G. Briggs
bioRxiv 2021.01.14.426695; doi: https://doi.org/10.1101/2021.01.14.426695
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