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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants

Zijun Wang, Fabian Schmidt, Yiska Weisblum, Frauke Muecksch, Christopher O. Barnes, Shlomo Finkin, Dennis Schaefer-Babajew, Melissa Cipolla, Christian Gaebler, Jenna A. Lieberman, Thiago Y. Oliveira, Zhi Yang, Morgan E. Abernathy, Kathryn E. Huey-Tubman, Arlene Hurley, Martina Turroja, Kamille A. West, Kristie Gordon, Katrina G. Millard, Victor Ramos, Justin Da Silva, Jianliang Xu, Robert A. Colbert, Roshni Patel, Juan Dizon, Cecille Unson-O’Brien, Irina Shimeliovich, Anna Gazumyan, Marina Caskey, Pamela J. Bjorkman, Rafael Casellas, Theodora Hatziioannou, Paul D. Bieniasz, Michel C. Nussenzweig
doi: https://doi.org/10.1101/2021.01.15.426911
Zijun Wang
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Fabian Schmidt
2Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA
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Yiska Weisblum
2Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA
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Frauke Muecksch
2Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA
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Christopher O. Barnes
3Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA
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Shlomo Finkin
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Dennis Schaefer-Babajew
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Melissa Cipolla
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Christian Gaebler
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Jenna A. Lieberman
4Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
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Thiago Y. Oliveira
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Zhi Yang
3Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA
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Morgan E. Abernathy
3Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA
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Kathryn E. Huey-Tubman
3Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA
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Arlene Hurley
5Hospital Program Direction, The Rockefeller University, New York, NY 10065, USA
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Martina Turroja
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Kamille A. West
6Department of Transfusion Medicine, National Institutes of Health Clinical Center, Bethesda, MD 20892.
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Kristie Gordon
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Katrina G. Millard
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Victor Ramos
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Justin Da Silva
2Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA
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Jianliang Xu
4Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
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Robert A. Colbert
7Pediatric Translational Research Branch and Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
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Roshni Patel
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Juan Dizon
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Cecille Unson-O’Brien
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Irina Shimeliovich
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Anna Gazumyan
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Marina Caskey
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
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Pamela J. Bjorkman
3Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA
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  • For correspondence: pbieniasz@rockefeller.edu bjorkman@caltech.edu rafael.casellas@nih.gov thatziio@rockefeller.edu nussen@rockefeller.edu
Rafael Casellas
4Lymphocyte Nuclear Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892.
8The NIH Regulome Project, National Institutes of Health, Bethesda, MD 20892.
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  • For correspondence: pbieniasz@rockefeller.edu bjorkman@caltech.edu rafael.casellas@nih.gov thatziio@rockefeller.edu nussen@rockefeller.edu
Theodora Hatziioannou
2Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA
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  • For correspondence: pbieniasz@rockefeller.edu bjorkman@caltech.edu rafael.casellas@nih.gov thatziio@rockefeller.edu nussen@rockefeller.edu
Paul D. Bieniasz
2Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA
9Howard Hughes Medical Institute
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  • For correspondence: pbieniasz@rockefeller.edu bjorkman@caltech.edu rafael.casellas@nih.gov thatziio@rockefeller.edu nussen@rockefeller.edu
Michel C. Nussenzweig
1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA
9Howard Hughes Medical Institute
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  • For correspondence: pbieniasz@rockefeller.edu bjorkman@caltech.edu rafael.casellas@nih.gov thatziio@rockefeller.edu nussen@rockefeller.edu
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Posted January 30, 2021.
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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
Zijun Wang, Fabian Schmidt, Yiska Weisblum, Frauke Muecksch, Christopher O. Barnes, Shlomo Finkin, Dennis Schaefer-Babajew, Melissa Cipolla, Christian Gaebler, Jenna A. Lieberman, Thiago Y. Oliveira, Zhi Yang, Morgan E. Abernathy, Kathryn E. Huey-Tubman, Arlene Hurley, Martina Turroja, Kamille A. West, Kristie Gordon, Katrina G. Millard, Victor Ramos, Justin Da Silva, Jianliang Xu, Robert A. Colbert, Roshni Patel, Juan Dizon, Cecille Unson-O’Brien, Irina Shimeliovich, Anna Gazumyan, Marina Caskey, Pamela J. Bjorkman, Rafael Casellas, Theodora Hatziioannou, Paul D. Bieniasz, Michel C. Nussenzweig
bioRxiv 2021.01.15.426911; doi: https://doi.org/10.1101/2021.01.15.426911
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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
Zijun Wang, Fabian Schmidt, Yiska Weisblum, Frauke Muecksch, Christopher O. Barnes, Shlomo Finkin, Dennis Schaefer-Babajew, Melissa Cipolla, Christian Gaebler, Jenna A. Lieberman, Thiago Y. Oliveira, Zhi Yang, Morgan E. Abernathy, Kathryn E. Huey-Tubman, Arlene Hurley, Martina Turroja, Kamille A. West, Kristie Gordon, Katrina G. Millard, Victor Ramos, Justin Da Silva, Jianliang Xu, Robert A. Colbert, Roshni Patel, Juan Dizon, Cecille Unson-O’Brien, Irina Shimeliovich, Anna Gazumyan, Marina Caskey, Pamela J. Bjorkman, Rafael Casellas, Theodora Hatziioannou, Paul D. Bieniasz, Michel C. Nussenzweig
bioRxiv 2021.01.15.426911; doi: https://doi.org/10.1101/2021.01.15.426911

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