SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

Constantinos Kurt Wibmer; Frances Ayres; Tandile Hermanus; Mashudu Madzivhandila; Prudence Kgagudi; Bronwen E. Lambson; Marion Vermeulen; Karin van den Berg; Theresa Rossouw; Michael Boswell; Veronica Ueckermann; Susan Meiring; Anne von Gottberg; Cheryl Cohen; Lynn Morris; Jinal N. Bhiman; Penny L. Moore

doi:10.1101/2021.01.18.427166

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SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

View ORCID ProfileConstantinos Kurt Wibmer, Frances Ayres, Tandile Hermanus, Mashudu Madzivhandila, Prudence Kgagudi, Bronwen E. Lambson, Marion Vermeulen, Karin van den Berg, View ORCID ProfileTheresa Rossouw, Michael Boswell, View ORCID ProfileVeronica Ueckermann, View ORCID ProfileSusan Meiring, View ORCID ProfileAnne von Gottberg, View ORCID ProfileCheryl Cohen, Lynn Morris, View ORCID ProfileJinal N. Bhiman, View ORCID ProfilePenny L. Moore

doi: https://doi.org/10.1101/2021.01.18.427166

Constantinos Kurt Wibmer

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

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Frances Ayres

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

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Tandile Hermanus

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

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Mashudu Madzivhandila

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

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Prudence Kgagudi

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

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Bronwen E. Lambson

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

2School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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Marion Vermeulen

3South African National Blood Service, Weltevreden Park, South Africa.

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Karin van den Berg

3South African National Blood Service, Weltevreden Park, South Africa.

4Division of Clinical Haematology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa

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Theresa Rossouw

5Department of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

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Michael Boswell

6Division for Infectious Diseases, Department of Internal Medicine, Steve Biko Academic Hospital and University of Pretoria, Pretoria, South Africa

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Veronica Ueckermann

6Division for Infectious Diseases, Department of Internal Medicine, Steve Biko Academic Hospital and University of Pretoria, Pretoria, South Africa

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Susan Meiring

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

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Anne von Gottberg

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

2School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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Cheryl Cohen

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

7School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg

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Lynn Morris

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

2School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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Jinal N. Bhiman

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

2School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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Penny L. Moore

1National Institute for Communicable Diseases (NICD) of the National Health Laboratory Service (NHLS), Johannesburg, South Africa.

2School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

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For correspondence: pennym@nicd.ac.za

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Posted January 19, 2021.

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SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

Constantinos Kurt Wibmer, Frances Ayres, Tandile Hermanus, Mashudu Madzivhandila, Prudence Kgagudi, Bronwen E. Lambson, Marion Vermeulen, Karin van den Berg, Theresa Rossouw, Michael Boswell, Veronica Ueckermann, Susan Meiring, Anne von Gottberg, Cheryl Cohen, Lynn Morris, Jinal N. Bhiman, Penny L. Moore

bioRxiv 2021.01.18.427166; doi: https://doi.org/10.1101/2021.01.18.427166

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