Article Information
History
- January 19, 2021.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Shanna Dewaele1,2,5,
- Louis Delhaye1,2,4,5,
- Boel De Paepe3,
- Eric De Bony1,2,5,
- Jilke De Wilde1,2,5,6,
- Katrien Vanderheyden1,2,5,
- Jasper Anckaert1,2,5,
- Nurten Yigit1,2,5,
- Eveline Vanden Eynde1,2,5,
- Fariba Nemati7,
- Didier Decaudin7,
- Aart Jochemsen9,
- Eleonora Leucci10,11,
- Jo Vandesompele1,2,5,
- Jo Van Dorpe2,6,
- Chris Marine11,
- Rudy Van Coster3,
- Sven Eyckerman2,4,5 and
- Pieter Mestdagh1,2,5,*
- 1OncoRNALab, Center for Medical Genetics (CMGG), Ghent University, Ghent, Belgium
- 2Cancer Research Institute Ghent (CRIG), Ghent, Belgium
- 3Department of Pediatrics, Division of Pediatric Neurology and Metabolism, Ghent University Hospital, Ghent, Belgium
- 4Center for Medical Biotechnology, VIB-Ghent University, Ghent, Belgium
- 5Department of Biomolecular Medicine, Ghent University, Ghent, Belgium
- 6Department of pathology, Ghent University Hospital, Ghent, Belgium
- 7Laboratory of Preclinical Investigation, Translational Research Department, Institut Curie, PSL University, Paris, France
- 8Department of Medical Oncology, Institut Curie, Paris, France
- 9Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, The Netherlands
- 10TRACE, LKI Leuven Cancer Institute, Leuven, Belgium
- 11Laboratory for RNA Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium
- ↵*Corresponding author Pieter Mestdagh, Corneel Heymanslaan 10, B-9000 Ghent, Belgium, +32 (0)9 332 5032, pieter.mestdagh{at}ugent.be.
Authors’ Contributions, P.M. conceived and supervised the project; S.D, L.D., B.D.P., E.D.B., J.D.W., K.V., N.Y, E.V.E. and S.E. designed and performed experiments; P.M., S.D., L.D., E.D.B., J.D.W., J.A analyzed the data; F.N., E.L. performed PDX experiments; A.J. provided cell lines; D.D., J.V.D., C.M, J.V., R.V.C., S.E. contributed technical support and resources; S.D. and P.M wrote the paper. All authors contributed to manuscript editing and approved the final draft.