Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Use Of Canine Olfactory Detection For COVID-19 Testing Study On U.A.E. Trained Detection Dog Sensitivity

View ORCID ProfileDominique Grandjean, Dana Humaid Al Marzooqi, Clothilde Lecoq-Julien, Quentin Muzzin, Hamad Katir Al Hammadi, Guillaume Alvergnat, Kalthoom Mohammad Al Blooshi, Salah khalifa Al Mazrouei, Mohammed Saeed Alhmoudi, Faisal Musleh Al Ahbabi, Yasser Saifallah Mohammed, Nasser Mohammed Alfalasi, Noor Majed Almheiri, Sumaya Mohamed Al Blooshi, Loïc Desquilbet
doi: https://doi.org/10.1101/2021.01.20.427105
Dominique Grandjean
aEcole Nationale Veterinaire d’Alfort, Universite Paris Est, 7 avenue du General de Gaulle, 94700 MAISONS-ALFORT (France)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Dominique Grandjean
Dana Humaid Al Marzooqi
bMinistry of Interior of the U.A.E., International Affairs Bureau
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Clothilde Lecoq-Julien
aEcole Nationale Veterinaire d’Alfort, Universite Paris Est, 7 avenue du General de Gaulle, 94700 MAISONS-ALFORT (France)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Quentin Muzzin
aEcole Nationale Veterinaire d’Alfort, Universite Paris Est, 7 avenue du General de Gaulle, 94700 MAISONS-ALFORT (France)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hamad Katir Al Hammadi
bMinistry of Interior of the U.A.E., International Affairs Bureau
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Guillaume Alvergnat
bMinistry of Interior of the U.A.E., International Affairs Bureau
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kalthoom Mohammad Al Blooshi
cMinistry of Health and Prevention of the U.A.E.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Salah khalifa Al Mazrouei
dGeneral Department of Protective Security and Emergency (U.A.E.), Dubaï K9 Unit
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mohammed Saeed Alhmoudi
bMinistry of Interior of the U.A.E., International Affairs Bureau
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Faisal Musleh Al Ahbabi
eAbu Dhabi Health Center (U.A.E.), Infectious diseases program
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yasser Saifallah Mohammed
fDubaï Health Authority (U.A.E.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nasser Mohammed Alfalasi
dGeneral Department of Protective Security and Emergency (U.A.E.), Dubaï K9 Unit
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Noor Majed Almheiri
cMinistry of Health and Prevention of the U.A.E.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sumaya Mohamed Al Blooshi
cMinistry of Health and Prevention of the U.A.E.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Loïc Desquilbet
aEcole Nationale Veterinaire d’Alfort, Universite Paris Est, 7 avenue du General de Gaulle, 94700 MAISONS-ALFORT (France)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: loic.desquilbet@vet-alfort.fr
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

ABSTRACT

This study aimed to evaluate the sensitivity of 21 dogs belonging to different United Arab Emirates (UAE) Ministry of Interior (MOI), trained for COVID-19 olfactory detection.

The study involved 17 explosives detection dogs, two cadaver detection dogs and two dogs with no previous detection training. Training lasted two weeks before starting the validation protocol. Sequential five and seven-cone line-ups were used with axillary sweat samples from symptomatic COVID-19 individuals (SARS-CoV-2 PCR positive) and from asymptomatic COVID-19 negative individuals (SARS-CoV-2 PCR negative). A total of 1368 trials were performed during validation, including 151 positive and 110 negative samples. Each line-up had one positive sample and at least one negative sample. The dog had to mark the positive sample, randomly positioned behind one of the cones. The dog, handler and data recorder were blinded to the positive sample location.

The calculated overall sensitivities were between 71% and 79% for three dogs, between83% and 87% for three other dogs, and equal to or higher than 90% for the remaining 15 dogs (more than two thirds of the 21 dogs).

After calculating the overall sensitivity for each dog using all line-ups, “matched” sensitivities were calculated only including line-ups containing COVID-19 positive and negative samples strictly comparable on confounding factors such as diabetes, anosmia, asthma, fever, body pain, diarrhoea, sex, hospital, method of sweat collection and sampling duration. Most of the time, the sensitivities increased after matching.

Pandemic conditions in the U.A.E., associated with the desire to use dogs as an efficient mass-pretesting tool has already led to the operational deployment of the study dogs.

Future studies will focus on comparatives fields-test results including the impact of the main COVID-19 comorbidities and other respiratory tract infections.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted January 20, 2021.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Use Of Canine Olfactory Detection For COVID-19 Testing Study On U.A.E. Trained Detection Dog Sensitivity
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Use Of Canine Olfactory Detection For COVID-19 Testing Study On U.A.E. Trained Detection Dog Sensitivity
Dominique Grandjean, Dana Humaid Al Marzooqi, Clothilde Lecoq-Julien, Quentin Muzzin, Hamad Katir Al Hammadi, Guillaume Alvergnat, Kalthoom Mohammad Al Blooshi, Salah khalifa Al Mazrouei, Mohammed Saeed Alhmoudi, Faisal Musleh Al Ahbabi, Yasser Saifallah Mohammed, Nasser Mohammed Alfalasi, Noor Majed Almheiri, Sumaya Mohamed Al Blooshi, Loïc Desquilbet
bioRxiv 2021.01.20.427105; doi: https://doi.org/10.1101/2021.01.20.427105
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Use Of Canine Olfactory Detection For COVID-19 Testing Study On U.A.E. Trained Detection Dog Sensitivity
Dominique Grandjean, Dana Humaid Al Marzooqi, Clothilde Lecoq-Julien, Quentin Muzzin, Hamad Katir Al Hammadi, Guillaume Alvergnat, Kalthoom Mohammad Al Blooshi, Salah khalifa Al Mazrouei, Mohammed Saeed Alhmoudi, Faisal Musleh Al Ahbabi, Yasser Saifallah Mohammed, Nasser Mohammed Alfalasi, Noor Majed Almheiri, Sumaya Mohamed Al Blooshi, Loïc Desquilbet
bioRxiv 2021.01.20.427105; doi: https://doi.org/10.1101/2021.01.20.427105

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Animal Behavior and Cognition
Subject Areas
All Articles
  • Animal Behavior and Cognition (2653)
  • Biochemistry (5286)
  • Bioengineering (3696)
  • Bioinformatics (15824)
  • Biophysics (7279)
  • Cancer Biology (5633)
  • Cell Biology (8118)
  • Clinical Trials (138)
  • Developmental Biology (4782)
  • Ecology (7548)
  • Epidemiology (2059)
  • Evolutionary Biology (10604)
  • Genetics (7746)
  • Genomics (10163)
  • Immunology (5223)
  • Microbiology (13962)
  • Molecular Biology (5399)
  • Neuroscience (30878)
  • Paleontology (217)
  • Pathology (883)
  • Pharmacology and Toxicology (1527)
  • Physiology (2262)
  • Plant Biology (5035)
  • Scientific Communication and Education (1045)
  • Synthetic Biology (1399)
  • Systems Biology (4156)
  • Zoology (814)