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Molecular basis of small-molecule binding to α-synuclein

Paul Robustelli, Alain Ibanez-de-Opakua, Cecily Campbell-Bezat, Fabrizio Giordanetto, Stefan Becker, Markus Zweckstetter, Albert C. Pan, David E. Shaw
doi: https://doi.org/10.1101/2021.01.22.426549
Paul Robustelli
1D. E. Shaw Research, New York, NY 10036, USA
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Alain Ibanez-de-Opakua
2German Center for Neurodegenerative Diseases (DZNE), 37077 Göttingen, Germany
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Cecily Campbell-Bezat
1D. E. Shaw Research, New York, NY 10036, USA
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Fabrizio Giordanetto
1D. E. Shaw Research, New York, NY 10036, USA
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Stefan Becker
3Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany
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Markus Zweckstetter
2German Center for Neurodegenerative Diseases (DZNE), 37077 Göttingen, Germany
3Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany
4DFG Research Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB), 37073 Göttingen, Germany
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  • For correspondence: Albert.Pan@DEShawResearch.com Markus.Zweckstetter@dzne.de David.Shaw@DEShawResearch.com
Albert C. Pan
1D. E. Shaw Research, New York, NY 10036, USA
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  • For correspondence: Albert.Pan@DEShawResearch.com Markus.Zweckstetter@dzne.de David.Shaw@DEShawResearch.com
David E. Shaw
1D. E. Shaw Research, New York, NY 10036, USA
5Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
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  • For correspondence: Albert.Pan@DEShawResearch.com Markus.Zweckstetter@dzne.de David.Shaw@DEShawResearch.com
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Posted January 24, 2021.
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Molecular basis of small-molecule binding to α-synuclein
Paul Robustelli, Alain Ibanez-de-Opakua, Cecily Campbell-Bezat, Fabrizio Giordanetto, Stefan Becker, Markus Zweckstetter, Albert C. Pan, David E. Shaw
bioRxiv 2021.01.22.426549; doi: https://doi.org/10.1101/2021.01.22.426549
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Molecular basis of small-molecule binding to α-synuclein
Paul Robustelli, Alain Ibanez-de-Opakua, Cecily Campbell-Bezat, Fabrizio Giordanetto, Stefan Becker, Markus Zweckstetter, Albert C. Pan, David E. Shaw
bioRxiv 2021.01.22.426549; doi: https://doi.org/10.1101/2021.01.22.426549

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