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mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants

Kai Wu, Anne P. Werner, Juan I. Moliva, Matthew Koch, Angela Choi, Guillaume B. E. Stewart-Jones, Hamilton Bennett, Seyhan Boyoglu-Barnum, Wei Shi, View ORCID ProfileBarney S. Graham, Andrea Carfi, Kizzmekia S. Corbett, Robert A. Seder, Darin K. Edwards
doi: https://doi.org/10.1101/2021.01.25.427948
Kai Wu
1Moderna Inc., Cambridge, MA, USA
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Anne P. Werner
2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
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Juan I. Moliva
2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
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Matthew Koch
1Moderna Inc., Cambridge, MA, USA
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Angela Choi
1Moderna Inc., Cambridge, MA, USA
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Guillaume B. E. Stewart-Jones
1Moderna Inc., Cambridge, MA, USA
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Hamilton Bennett
1Moderna Inc., Cambridge, MA, USA
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Seyhan Boyoglu-Barnum
2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
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Wei Shi
2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
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Barney S. Graham
2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
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  • ORCID record for Barney S. Graham
Andrea Carfi
1Moderna Inc., Cambridge, MA, USA
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Kizzmekia S. Corbett
2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
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Robert A. Seder
2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
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Darin K. Edwards
1Moderna Inc., Cambridge, MA, USA
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  • For correspondence: darin.edwards@modernatx.com
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Article Information

doi 
https://doi.org/10.1101/2021.01.25.427948
History 
  • January 25, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Kai Wu1,
  2. Anne P. Werner2,
  3. Juan I. Moliva2,
  4. Matthew Koch1,
  5. Angela Choi1,
  6. Guillaume B. E. Stewart-Jones1,
  7. Hamilton Bennett1,
  8. Seyhan Boyoglu-Barnum2,
  9. Wei Shi2,
  10. Barney S. Graham2,
  11. Andrea Carfi1,
  12. Kizzmekia S. Corbett2,
  13. Robert A. Seder2 and
  14. Darin K. Edwards1,*
  1. 1Moderna Inc., Cambridge, MA, USA
  2. 2National Institutes of Health, National Institute of Allergy and Infectious Diseases, Vaccine Research Center, Bethesda, MD, USA
  1. ↵* Corresponding author; email: darin.edwards{at}modernatx.com
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Posted January 25, 2021.
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mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants
Kai Wu, Anne P. Werner, Juan I. Moliva, Matthew Koch, Angela Choi, Guillaume B. E. Stewart-Jones, Hamilton Bennett, Seyhan Boyoglu-Barnum, Wei Shi, Barney S. Graham, Andrea Carfi, Kizzmekia S. Corbett, Robert A. Seder, Darin K. Edwards
bioRxiv 2021.01.25.427948; doi: https://doi.org/10.1101/2021.01.25.427948
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mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants
Kai Wu, Anne P. Werner, Juan I. Moliva, Matthew Koch, Angela Choi, Guillaume B. E. Stewart-Jones, Hamilton Bennett, Seyhan Boyoglu-Barnum, Wei Shi, Barney S. Graham, Andrea Carfi, Kizzmekia S. Corbett, Robert A. Seder, Darin K. Edwards
bioRxiv 2021.01.25.427948; doi: https://doi.org/10.1101/2021.01.25.427948

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