Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum

Gajanan N. Sapkal, Pragya D. Yadav, Raches Ella, Gururaj R. Deshpande, Rima R. Sahay, Nivedita Gupta, V Krishna Mohan, Priya Abraham, Samiran Panda, Balram Bhargava
doi: https://doi.org/10.1101/2021.01.26.426986
Gajanan N. Sapkal
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pragya D. Yadav
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: hellopragya22@gmail.com
Raches Ella
2Bharat Biotech International Limited, Genome Valley, Hyderabad, Telangana, India Pin-500078
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gururaj R. Deshpande
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rima R. Sahay
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nivedita Gupta
3Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
V Krishna Mohan
2Bharat Biotech International Limited, Genome Valley, Hyderabad, Telangana, India Pin-500078
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Priya Abraham
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India Pin-411021
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Samiran Panda
3Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Balram Bhargava
3Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

We performed the plaque reduction neutralization test (PRNT50) using sera collected from the 26 recipients of BBV152/COVAXIN™ against hCoV-19/India/20203522 (UK-variant) and hCoV27 19/India/2020Q111 (heterologous strain). A comparable neutralization activity of the vaccinated individuals sera showed against UK-variant and the heterologous strain with similar efficiency, dispel the uncertainty of possible neutralization escape.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
Back to top
PreviousNext
Posted January 26, 2021.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum
Gajanan N. Sapkal, Pragya D. Yadav, Raches Ella, Gururaj R. Deshpande, Rima R. Sahay, Nivedita Gupta, V Krishna Mohan, Priya Abraham, Samiran Panda, Balram Bhargava
bioRxiv 2021.01.26.426986; doi: https://doi.org/10.1101/2021.01.26.426986
Reddit logo Twitter logo Facebook logo LinkedIn logo Mendeley logo
Citation Tools
Neutralization of UK-variant VUI-202012/01 with COVAXIN vaccinated human serum
Gajanan N. Sapkal, Pragya D. Yadav, Raches Ella, Gururaj R. Deshpande, Rima R. Sahay, Nivedita Gupta, V Krishna Mohan, Priya Abraham, Samiran Panda, Balram Bhargava
bioRxiv 2021.01.26.426986; doi: https://doi.org/10.1101/2021.01.26.426986

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Molecular Biology
  • Microbiology
Subject Areas
All Articles
  • Animal Behavior and Cognition (4395)
  • Biochemistry (9613)
  • Bioengineering (7110)
  • Bioinformatics (24911)
  • Biophysics (12642)
  • Cancer Biology (9978)
  • Cell Biology (14375)
  • Clinical Trials (138)
  • Developmental Biology (7967)
  • Ecology (12131)
  • Epidemiology (2067)
  • Evolutionary Biology (16007)
  • Genetics (10937)
  • Genomics (14762)
  • Immunology (9886)
  • Microbiology (23701)
  • Molecular Biology (9491)
  • Neuroscience (50960)
  • Paleontology (370)
  • Pathology (1544)
  • Pharmacology and Toxicology (2688)
  • Physiology (4031)
  • Plant Biology (8677)
  • Scientific Communication and Education (1512)
  • Synthetic Biology (2402)
  • Systems Biology (6446)
  • Zoology (1346)