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A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques
Ahmed O. Hassan, Friederike Feldmann, Haiyan Zhao, David T. Curiel, Atsushi Okumura, Tsing-Lee Tang-Huau, James Brett Case, Kimberly Meade-White, Julie Callison, Jamie Lovaglio, Patrick W. Hanley, Dana P. Scott, Daved H. Fremont, View ORCID ProfileHeinz Feldmann, View ORCID ProfileMichael S. Diamond
doi: https://doi.org/10.1101/2021.01.26.428251
Ahmed O. Hassan
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Friederike Feldmann
2Rocky Mountain Veterinary Branch Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Haiyan Zhao
3Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA
David T. Curiel
4Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA
Atsushi Okumura
5Laboratory of Virology, Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Tsing-Lee Tang-Huau
5Laboratory of Virology, Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
James Brett Case
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Kimberly Meade-White
5Laboratory of Virology, Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Julie Callison
5Laboratory of Virology, Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Jamie Lovaglio
2Rocky Mountain Veterinary Branch Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Patrick W. Hanley
2Rocky Mountain Veterinary Branch Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Dana P. Scott
2Rocky Mountain Veterinary Branch Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Daved H. Fremont
3Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA
6Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA
7Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA
Heinz Feldmann
5Laboratory of Virology, Division of Intramural Research, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT, USA
Michael S. Diamond
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA
7Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA
Article usage
Posted January 26, 2021.
A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques
Ahmed O. Hassan, Friederike Feldmann, Haiyan Zhao, David T. Curiel, Atsushi Okumura, Tsing-Lee Tang-Huau, James Brett Case, Kimberly Meade-White, Julie Callison, Jamie Lovaglio, Patrick W. Hanley, Dana P. Scott, Daved H. Fremont, Heinz Feldmann, Michael S. Diamond
bioRxiv 2021.01.26.428251; doi: https://doi.org/10.1101/2021.01.26.428251
A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques
Ahmed O. Hassan, Friederike Feldmann, Haiyan Zhao, David T. Curiel, Atsushi Okumura, Tsing-Lee Tang-Huau, James Brett Case, Kimberly Meade-White, Julie Callison, Jamie Lovaglio, Patrick W. Hanley, Dana P. Scott, Daved H. Fremont, Heinz Feldmann, Michael S. Diamond
bioRxiv 2021.01.26.428251; doi: https://doi.org/10.1101/2021.01.26.428251
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