Phencyclidine-induced psychosis causes hypersynchronization and disruption of connectivity within prefrontal-hippocampal circuits that is rescued by antipsychotic drugs

Cristina Delgado-Sallent; Pau Nebot; Thomas Gener; Melina Timplalexi; Amanda B Fath; M Victoria Puig

doi:10.1101/2021.02.03.429582

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Phencyclidine-induced psychosis causes hypersynchronization and disruption of connectivity within prefrontal-hippocampal circuits that is rescued by antipsychotic drugs

View ORCID ProfileCristina Delgado-Sallent, View ORCID ProfilePau Nebot, View ORCID ProfileThomas Gener, Melina Timplalexi, View ORCID ProfileAmanda B Fath, View ORCID ProfileM Victoria Puig

doi: https://doi.org/10.1101/2021.02.03.429582

Cristina Delgado-Sallent

1Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, 08003 Barcelona, Spain

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ORCID record for Cristina Delgado-Sallent

Pau Nebot

1Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, 08003 Barcelona, Spain

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Thomas Gener

1Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, 08003 Barcelona, Spain

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Melina Timplalexi

1Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, 08003 Barcelona, Spain

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Amanda B Fath

1Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, 08003 Barcelona, Spain

2Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139 USA

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M Victoria Puig

1Hospital del Mar Medical Research Institute, Barcelona Biomedical Research Park, 08003 Barcelona, Spain

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For correspondence: [email protected]

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Posted February 05, 2021.

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Phencyclidine-induced psychosis causes hypersynchronization and disruption of connectivity within prefrontal-hippocampal circuits that is rescued by antipsychotic drugs

Cristina Delgado-Sallent, Pau Nebot, Thomas Gener, Melina Timplalexi, Amanda B Fath, M Victoria Puig

bioRxiv 2021.02.03.429582; doi: https://doi.org/10.1101/2021.02.03.429582

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Phencyclidine-induced psychosis causes hypersynchronization and disruption of connectivity within prefrontal-hippocampal circuits that is rescued by antipsychotic drugs

Cristina Delgado-Sallent, Pau Nebot, Thomas Gener, Melina Timplalexi, Amanda B Fath, M Victoria Puig

bioRxiv 2021.02.03.429582; doi: https://doi.org/10.1101/2021.02.03.429582

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