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Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility

View ORCID ProfileJennifer Zou, Shyam Gopalakrishnan, Clarissa C. Parker, Jerome Nicod, Richard Mott, Na Cai, Arimantas Lionikas, Robert W Davies, View ORCID ProfileAbraham A. Palmer, Jonathan Flint
doi: https://doi.org/10.1101/2021.02.05.429998
Jennifer Zou
1Department of Computer Science, University of California, Los Angeles, CA 90024, USA
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  • ORCID record for Jennifer Zou
Shyam Gopalakrishnan
2GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade, Copenhagen, Denmark
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Clarissa C. Parker
3Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, 05753, USA
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Jerome Nicod
4The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK
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Richard Mott
5UCL Genetics Institute, UCL Department of Genetics, Evolution & Environment, London WC1E 6BT, UK
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Na Cai
6Helmoltz Pioneer Campus, Helmholtz Zentrum Muenchen, 85764 Neuherberg, Germany
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Arimantas Lionikas
7School of Medicine, Medical Sciences, and Nutrition, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, UK AB24 3FX, UK
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Robert W Davies
8Department of Statistics, University of Oxford, Oxford, UK
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Abraham A. Palmer
9Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA Institute for Genomic Medicine, University of California San Diego, La Jolla, CA 92093, USA
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  • ORCID record for Abraham A. Palmer
  • For correspondence: jflint@mednet.ucla.edu aap@ucsd.edu
Jonathan Flint
10Department of Biobehavioral Sciences, University of California, Los Angeles, CA 90024, USA
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  • For correspondence: jflint@mednet.ucla.edu aap@ucsd.edu
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Article Information

doi 
https://doi.org/10.1101/2021.02.05.429998
History 
  • February 7, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. Jennifer Zou1,
  2. Shyam Gopalakrishnan2,
  3. Clarissa C. Parker3,
  4. Jerome Nicod4,
  5. Richard Mott5,
  6. Na Cai6,
  7. Arimantas Lionikas7,
  8. Robert W Davies8,
  9. Abraham A. Palmer9,* and
  10. Jonathan Flint10,*
  1. 1Department of Computer Science, University of California, Los Angeles, CA 90024, USA
  2. 2GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade, Copenhagen, Denmark
  3. 3Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, 05753, USA
  4. 4The Francis Crick Institute, 1 Midland Road, London, NW1 1AT, UK
  5. 5UCL Genetics Institute, UCL Department of Genetics, Evolution & Environment, London WC1E 6BT, UK
  6. 6Helmoltz Pioneer Campus, Helmholtz Zentrum Muenchen, 85764 Neuherberg, Germany
  7. 7School of Medicine, Medical Sciences, and Nutrition, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, UK AB24 3FX, UK
  8. 8Department of Statistics, University of Oxford, Oxford, UK
  9. 9Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA Institute for Genomic Medicine, University of California San Diego, La Jolla, CA 92093, USA
  10. 10Department of Biobehavioral Sciences, University of California, Los Angeles, CA 90024, USA
  1. ↵*Correspondence: Jonathan Flint jflint{at}mednet.ucla.edu and Abraham Palmer aap{at}ucsd.edu
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Posted February 07, 2021.
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Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility
Jennifer Zou, Shyam Gopalakrishnan, Clarissa C. Parker, Jerome Nicod, Richard Mott, Na Cai, Arimantas Lionikas, Robert W Davies, Abraham A. Palmer, Jonathan Flint
bioRxiv 2021.02.05.429998; doi: https://doi.org/10.1101/2021.02.05.429998
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Analysis of independent cohorts of outbred CFW mice reveals novel loci for behavioral and physiological traits and identifies factors determining reproducibility
Jennifer Zou, Shyam Gopalakrishnan, Clarissa C. Parker, Jerome Nicod, Richard Mott, Na Cai, Arimantas Lionikas, Robert W Davies, Abraham A. Palmer, Jonathan Flint
bioRxiv 2021.02.05.429998; doi: https://doi.org/10.1101/2021.02.05.429998

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