Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Numerical calculation of the light propagation in tapered optical fibers for optical neural interfaces

View ORCID ProfileRosa Mach-Batlle, Marco Pisanello, View ORCID ProfileFilippo Pisano, Massimo De Vittorio, View ORCID ProfileFerruccio Pisanello, View ORCID ProfileCristian Ciracì
doi: https://doi.org/10.1101/2021.02.08.430223
Rosa Mach-Batlle
†Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia, Via Barsanti 14, 73010 Arnesano (LE), Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rosa Mach-Batlle
  • For correspondence: rosa.machbatlle@iit.it cristian.ciraci@iit.it
Marco Pisanello
†Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia, Via Barsanti 14, 73010 Arnesano (LE), Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Filippo Pisano
†Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia, Via Barsanti 14, 73010 Arnesano (LE), Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Filippo Pisano
Massimo De Vittorio
†Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia, Via Barsanti 14, 73010 Arnesano (LE), Italy
‡Dipartimento di Ingegneria dell’Innovazione, Università del Salento, Lecce, Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ferruccio Pisanello
†Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia, Via Barsanti 14, 73010 Arnesano (LE), Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ferruccio Pisanello
Cristian Ciracì
†Center for Biomolecular Nanotechnologies, Istituto Italiano di Tecnologia, Via Barsanti 14, 73010 Arnesano (LE), Italy
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Cristian Ciracì
  • For correspondence: rosa.machbatlle@iit.it cristian.ciraci@iit.it
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

As implantable optical systems recently enabled new approaches to study the brain with optical radiations, tapered optical fibers emerged as promising implantable waveguides to deliver and collect light from sub-cortical structures of the mouse brain. They rely on a specific feature of multimodal fiber optics: as the waveguide narrows, the number of guided modes decreases and the radiation can gradually couple with the environment. This happens along a taper segment whose length can be tailored to match with the depth of functional structures of the mouse brain, and can extend for a few millimeters. This anatomical requirement results in optical systems with an active area very long compared to the wavelength of the light they guide and their behaviour is typically estimated by ray tracing simulations, being finite-elements methods computationally too heavy. Here we present a computational technique that exploits the beam-envelope method and the cylindrical symmetry of the fibers to provide an efficient and exact calculation of the electric field along the fibers, which may enable the design of neural interfaces optimized to meet different goals.

Competing Interest Statement

Disclosures: M.D.V. and F. Pisanello are founders and hold private equity in Optogenix, a company that develops, produces and sells technologies to deliver light into the brain. Tapered fibers commercially available from Optogenix were used as tools in the research.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Back to top
PreviousNext
Posted February 09, 2021.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Numerical calculation of the light propagation in tapered optical fibers for optical neural interfaces
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Numerical calculation of the light propagation in tapered optical fibers for optical neural interfaces
Rosa Mach-Batlle, Marco Pisanello, Filippo Pisano, Massimo De Vittorio, Ferruccio Pisanello, Cristian Ciracì
bioRxiv 2021.02.08.430223; doi: https://doi.org/10.1101/2021.02.08.430223
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Numerical calculation of the light propagation in tapered optical fibers for optical neural interfaces
Rosa Mach-Batlle, Marco Pisanello, Filippo Pisano, Massimo De Vittorio, Ferruccio Pisanello, Cristian Ciracì
bioRxiv 2021.02.08.430223; doi: https://doi.org/10.1101/2021.02.08.430223

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (4114)
  • Biochemistry (8816)
  • Bioengineering (6519)
  • Bioinformatics (23464)
  • Biophysics (11792)
  • Cancer Biology (9209)
  • Cell Biology (13325)
  • Clinical Trials (138)
  • Developmental Biology (7439)
  • Ecology (11412)
  • Epidemiology (2066)
  • Evolutionary Biology (15152)
  • Genetics (10439)
  • Genomics (14044)
  • Immunology (9172)
  • Microbiology (22159)
  • Molecular Biology (8813)
  • Neuroscience (47575)
  • Paleontology (350)
  • Pathology (1429)
  • Pharmacology and Toxicology (2492)
  • Physiology (3730)
  • Plant Biology (8082)
  • Scientific Communication and Education (1437)
  • Synthetic Biology (2221)
  • Systems Biology (6039)
  • Zoology (1253)