Fluctuations in TCR and pMHC interactions regulate T cell activation

Joseph R. Egan; Enas Abu-Shah; Omer Dushek; Tim Elliott; Ben D. MacArthur

doi:10.1101/2021.02.09.430441

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Fluctuations in TCR and pMHC interactions regulate T cell activation

View ORCID ProfileJoseph R. Egan, View ORCID ProfileEnas Abu-Shah, View ORCID ProfileOmer Dushek, View ORCID ProfileTim Elliott, View ORCID ProfileBen D. MacArthur

doi: https://doi.org/10.1101/2021.02.09.430441

Joseph R. Egan

aMathematical Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom

bCentre for Cancer Immunology, University Hospital Southampton, Southampton SO16 6YD, United Kingdom

cInstitute for Life Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom

dSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom

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ORCID record for Joseph R. Egan
For correspondence: j.r.egan@soton.ac.uk

Enas Abu-Shah

dSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom

eKennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, United Kingdom

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Omer Dushek

dSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom

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Tim Elliott

bCentre for Cancer Immunology, University Hospital Southampton, Southampton SO16 6YD, United Kingdom

cInstitute for Life Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom

fNuffield Department of Medicine, University of Oxford, Oxford OX3 7BN, United Kingdom

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Ben D. MacArthur

aMathematical Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom

cInstitute for Life Sciences, University of Southampton, Southampton SO17 1BJ, United Kingdom

gCentre for Human Development, Stem Cells and Regeneration, University of Southampton, Southampton SO17 1BJ, United Kingdom

hAlan Turing Institute, London NW1 2DB, United Kingdom

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Posted July 05, 2021.

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Fluctuations in TCR and pMHC interactions regulate T cell activation

Joseph R. Egan, Enas Abu-Shah, Omer Dushek, Tim Elliott, Ben D. MacArthur

bioRxiv 2021.02.09.430441; doi: https://doi.org/10.1101/2021.02.09.430441

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Fluctuations in TCR and pMHC interactions regulate T cell activation

Joseph R. Egan, Enas Abu-Shah, Omer Dushek, Tim Elliott, Ben D. MacArthur

bioRxiv 2021.02.09.430441; doi: https://doi.org/10.1101/2021.02.09.430441

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