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Single-Domain SARS-CoV-2 S1 and RBD Antibodies Isolated from Immunized Llama Effectively Bind Targets of the Wuhan, UK, and South African Strains in vitro

Divora Yemane, Ivan Lu, Winson Tiahjono, Lauren Rubidoux, Abbas Hussain, John C. Cancilla, Erika Duggan, Nathan C. Shaner, Nobuki Nakanishi, Jiwu Wang
doi: https://doi.org/10.1101/2021.02.15.431198
Divora Yemane
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
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Ivan Lu
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
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Winson Tiahjono
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
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Lauren Rubidoux
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
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Abbas Hussain
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
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John C. Cancilla
2Scintillon Institute, 6868 Nancy Ridge Drive, San Diego, CA 92121
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Erika Duggan
2Scintillon Institute, 6868 Nancy Ridge Drive, San Diego, CA 92121
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Nathan C. Shaner
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
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Nobuki Nakanishi
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
2Scintillon Institute, 6868 Nancy Ridge Drive, San Diego, CA 92121
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Jiwu Wang
1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
2Scintillon Institute, 6868 Nancy Ridge Drive, San Diego, CA 92121
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  • For correspondence: jiwuwang@allelebiotech.com
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Article Information

doi 
https://doi.org/10.1101/2021.02.15.431198
History 
  • February 16, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. Divora Yemane1,*,
  2. Ivan Lu1,*,
  3. Winson Tiahjono1,
  4. Lauren Rubidoux1,
  5. Abbas Hussain1,
  6. John C. Cancilla2,
  7. Erika Duggan2,
  8. Nathan C. Shaner1,
  9. Nobuki Nakanishi1,2 and
  10. Jiwu Wang1,2,#
  1. 1Allele Biotechnology and Pharmaceuticals, Inc., 6404 Nancy Ridge Drive, San Diego, CA 92121
  2. 2Scintillon Institute, 6868 Nancy Ridge Drive, San Diego, CA 92121
  1. ↵#Corresponding Author:
    Jiwu Wang, Ph.D. jiwuwang{at}allelebiotech.com
  1. ↵* These authors contributed equally.

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Posted February 16, 2021.
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Single-Domain SARS-CoV-2 S1 and RBD Antibodies Isolated from Immunized Llama Effectively Bind Targets of the Wuhan, UK, and South African Strains in vitro
Divora Yemane, Ivan Lu, Winson Tiahjono, Lauren Rubidoux, Abbas Hussain, John C. Cancilla, Erika Duggan, Nathan C. Shaner, Nobuki Nakanishi, Jiwu Wang
bioRxiv 2021.02.15.431198; doi: https://doi.org/10.1101/2021.02.15.431198
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Single-Domain SARS-CoV-2 S1 and RBD Antibodies Isolated from Immunized Llama Effectively Bind Targets of the Wuhan, UK, and South African Strains in vitro
Divora Yemane, Ivan Lu, Winson Tiahjono, Lauren Rubidoux, Abbas Hussain, John C. Cancilla, Erika Duggan, Nathan C. Shaner, Nobuki Nakanishi, Jiwu Wang
bioRxiv 2021.02.15.431198; doi: https://doi.org/10.1101/2021.02.15.431198

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