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A glycan gate controls opening of the SARS-CoV-2 spike protein
View ORCID ProfileTerra Sztain, Surl-Hee Ahn, Anthony T. Bogetti, View ORCID ProfileLorenzo Casalino, Jory A. Goldsmith, View ORCID ProfileEvan Seitz, Ryan S. McCool, Fiona L. Kearns, Francisco Acosta-Reyes, Suvrajit Maji, Ghoncheh Mashayekhi, J. Andrew McCammon, Abbas Ourmazd, Joachim Frank, Jason S. McLellan, Lillian T. Chong, View ORCID ProfileRommie E. Amaro
doi: https://doi.org/10.1101/2021.02.15.431212
Terra Sztain
1Department of Chemistry and Biochemistry, UC San Diego, La Jolla, CA 92093
Surl-Hee Ahn
1Department of Chemistry and Biochemistry, UC San Diego, La Jolla, CA 92093
Anthony T. Bogetti
2Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260
Lorenzo Casalino
1Department of Chemistry and Biochemistry, UC San Diego, La Jolla, CA 92093
Jory A. Goldsmith
3Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712
Evan Seitz
4Department of Biological Sciences, Columbia University, New York, NY, 10032, USA
Ryan S. McCool
3Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712
Fiona L. Kearns
1Department of Chemistry and Biochemistry, UC San Diego, La Jolla, CA 92093
Francisco Acosta-Reyes
5Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA
Suvrajit Maji
5Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA
Ghoncheh Mashayekhi
6Department of Physics, University of Wisconsin-Milwaukee, 3135 N. Maryland Ave, Milwaukee, WI 53211, USA
J. Andrew McCammon
1Department of Chemistry and Biochemistry, UC San Diego, La Jolla, CA 92093
7Department of Pharmacology, UC San Diego, La Jolla, CA 92093
Abbas Ourmazd
6Department of Physics, University of Wisconsin-Milwaukee, 3135 N. Maryland Ave, Milwaukee, WI 53211, USA
Joachim Frank
4Department of Biological Sciences, Columbia University, New York, NY, 10032, USA
5Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA
Jason S. McLellan
3Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712
Lillian T. Chong
2Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260
Rommie E. Amaro
1Department of Chemistry and Biochemistry, UC San Diego, La Jolla, CA 92093
Posted May 17, 2021.
A glycan gate controls opening of the SARS-CoV-2 spike protein
Terra Sztain, Surl-Hee Ahn, Anthony T. Bogetti, Lorenzo Casalino, Jory A. Goldsmith, Evan Seitz, Ryan S. McCool, Fiona L. Kearns, Francisco Acosta-Reyes, Suvrajit Maji, Ghoncheh Mashayekhi, J. Andrew McCammon, Abbas Ourmazd, Joachim Frank, Jason S. McLellan, Lillian T. Chong, Rommie E. Amaro
bioRxiv 2021.02.15.431212; doi: https://doi.org/10.1101/2021.02.15.431212
A glycan gate controls opening of the SARS-CoV-2 spike protein
Terra Sztain, Surl-Hee Ahn, Anthony T. Bogetti, Lorenzo Casalino, Jory A. Goldsmith, Evan Seitz, Ryan S. McCool, Fiona L. Kearns, Francisco Acosta-Reyes, Suvrajit Maji, Ghoncheh Mashayekhi, J. Andrew McCammon, Abbas Ourmazd, Joachim Frank, Jason S. McLellan, Lillian T. Chong, Rommie E. Amaro
bioRxiv 2021.02.15.431212; doi: https://doi.org/10.1101/2021.02.15.431212
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