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501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab in vitro

Haolin Liu, Pengcheng Wei, Qianqian Zhang, Zhongzhou Chen, Katja Aviszus, Walter Downing, Shelley Peterson, Lyndon Reynoso, Gregory P. Downey, Stephen K. Frankel, John Kappler, Philippa Marrack, Gongyi Zhang
doi: https://doi.org/10.1101/2021.02.16.431305
Haolin Liu
1Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206, USA and Department of Immunology and Microbiology, School of Medicine, Anschutz Medical Center, University of Colorado, Aurora, CO 80216, USA
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  • For correspondence: Liuh@NJhealth.org Marrackp@NJhealth.org Zhangg@NJhealth.org
Pengcheng Wei
1Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206, USA and Department of Immunology and Microbiology, School of Medicine, Anschutz Medical Center, University of Colorado, Aurora, CO 80216, USA
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Qianqian Zhang
2State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agriculture University, Beijing 100193, People’s Republic of China
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Zhongzhou Chen
2State Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agriculture University, Beijing 100193, People’s Republic of China
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Katja Aviszus
1Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206, USA and Department of Immunology and Microbiology, School of Medicine, Anschutz Medical Center, University of Colorado, Aurora, CO 80216, USA
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Walter Downing
3Department of Nursing, National Jewish Health, Denver, CO80206, USA
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Shelley Peterson
3Department of Nursing, National Jewish Health, Denver, CO80206, USA
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Lyndon Reynoso
4Department of Pharmacy, National Jewish Health, Denver, CO80206, USA
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Gregory P. Downey
5Department of Medicine, National Jewish Health, Denver, CO 80206, USA
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Stephen K. Frankel
5Department of Medicine, National Jewish Health, Denver, CO 80206, USA
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John Kappler
1Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206, USA and Department of Immunology and Microbiology, School of Medicine, Anschutz Medical Center, University of Colorado, Aurora, CO 80216, USA
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Philippa Marrack
1Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206, USA and Department of Immunology and Microbiology, School of Medicine, Anschutz Medical Center, University of Colorado, Aurora, CO 80216, USA
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  • For correspondence: Liuh@NJhealth.org Marrackp@NJhealth.org Zhangg@NJhealth.org
Gongyi Zhang
1Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO 80206, USA and Department of Immunology and Microbiology, School of Medicine, Anschutz Medical Center, University of Colorado, Aurora, CO 80216, USA
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  • For correspondence: Liuh@NJhealth.org Marrackp@NJhealth.org Zhangg@NJhealth.org
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Posted February 16, 2021.
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501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab in vitro
Haolin Liu, Pengcheng Wei, Qianqian Zhang, Zhongzhou Chen, Katja Aviszus, Walter Downing, Shelley Peterson, Lyndon Reynoso, Gregory P. Downey, Stephen K. Frankel, John Kappler, Philippa Marrack, Gongyi Zhang
bioRxiv 2021.02.16.431305; doi: https://doi.org/10.1101/2021.02.16.431305
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501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab in vitro
Haolin Liu, Pengcheng Wei, Qianqian Zhang, Zhongzhou Chen, Katja Aviszus, Walter Downing, Shelley Peterson, Lyndon Reynoso, Gregory P. Downey, Stephen K. Frankel, John Kappler, Philippa Marrack, Gongyi Zhang
bioRxiv 2021.02.16.431305; doi: https://doi.org/10.1101/2021.02.16.431305

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