Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

E484K mutation in SARS-CoV-2 RBD enhances binding affinity with hACE2 but reduces interactions with neutralizing antibodies and nanobodies: Binding free energy calculation studies

Wei Bu Wang, Yu Liang, Yu Qin Jin, Jing Zhang, View ORCID ProfileJi Guo Su, Qi Ming Li
doi: https://doi.org/10.1101/2021.02.17.431566
Wei Bu Wang
1Key Laboratory for Microstructural Material Physics of Hebei Province, School of Science, Yanshan University, Qinhuangdao 066004, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yu Liang
2The Sixth Laboratory, National Vaccine and Serum Institute, Beijing 101111, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yu Qin Jin
2The Sixth Laboratory, National Vaccine and Serum Institute, Beijing 101111, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jing Zhang
2The Sixth Laboratory, National Vaccine and Serum Institute, Beijing 101111, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ji Guo Su
1Key Laboratory for Microstructural Material Physics of Hebei Province, School of Science, Yanshan University, Qinhuangdao 066004, China
2The Sixth Laboratory, National Vaccine and Serum Institute, Beijing 101111, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ji Guo Su
  • For correspondence: liqiming189@163.com jiguosu@ysu.edu.cn
Qi Ming Li
2The Sixth Laboratory, National Vaccine and Serum Institute, Beijing 101111, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: liqiming189@163.com jiguosu@ysu.edu.cn
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading
  • Supplemental Table S1[supplements/431566_file02.docx]
Back to top
PreviousNext
Posted February 17, 2021.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
E484K mutation in SARS-CoV-2 RBD enhances binding affinity with hACE2 but reduces interactions with neutralizing antibodies and nanobodies: Binding free energy calculation studies
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
E484K mutation in SARS-CoV-2 RBD enhances binding affinity with hACE2 but reduces interactions with neutralizing antibodies and nanobodies: Binding free energy calculation studies
Wei Bu Wang, Yu Liang, Yu Qin Jin, Jing Zhang, Ji Guo Su, Qi Ming Li
bioRxiv 2021.02.17.431566; doi: https://doi.org/10.1101/2021.02.17.431566
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
E484K mutation in SARS-CoV-2 RBD enhances binding affinity with hACE2 but reduces interactions with neutralizing antibodies and nanobodies: Binding free energy calculation studies
Wei Bu Wang, Yu Liang, Yu Qin Jin, Jing Zhang, Ji Guo Su, Qi Ming Li
bioRxiv 2021.02.17.431566; doi: https://doi.org/10.1101/2021.02.17.431566

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Bioinformatics
Subject Areas
All Articles
  • Animal Behavior and Cognition (2652)
  • Biochemistry (5278)
  • Bioengineering (3690)
  • Bioinformatics (15817)
  • Biophysics (7267)
  • Cancer Biology (5633)
  • Cell Biology (8109)
  • Clinical Trials (138)
  • Developmental Biology (4777)
  • Ecology (7535)
  • Epidemiology (2059)
  • Evolutionary Biology (10594)
  • Genetics (7740)
  • Genomics (10153)
  • Immunology (5213)
  • Microbiology (13940)
  • Molecular Biology (5395)
  • Neuroscience (30829)
  • Paleontology (216)
  • Pathology (882)
  • Pharmacology and Toxicology (1527)
  • Physiology (2259)
  • Plant Biology (5031)
  • Scientific Communication and Education (1043)
  • Synthetic Biology (1394)
  • Systems Biology (4153)
  • Zoology (813)