New Results
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2
View ORCID ProfileCatherine F Hatton, View ORCID ProfileRachel A Botting, View ORCID ProfileMaria Emilia Dueñas, View ORCID ProfileIram J Haq, View ORCID ProfileBernard Verdon, View ORCID ProfileBenjamin J Thompson, View ORCID ProfileJarmila Stremenova Spegarova, View ORCID ProfileFlorian Gothe, View ORCID ProfileEmily Stephenson, View ORCID ProfileAaron I Gardner, View ORCID ProfileSandra Murphy, View ORCID ProfileJonathan Scott, View ORCID ProfileJames P Garnett, View ORCID ProfileSean Carrie, Jason Powell, C M Anjam Khan, Lei Huang, Rafiqul Hussain, View ORCID ProfileJonathan Coxhead, View ORCID ProfileTracey Davey, View ORCID ProfileA John Simpson, View ORCID ProfileMuzlifah Haniffa, View ORCID ProfileSophie Hambleton, View ORCID ProfileMalcolm Brodlie, View ORCID ProfileChris Ward, View ORCID ProfileMatthias Trost, View ORCID ProfileGary Reynolds, View ORCID ProfileChristopher J A Duncan
doi: https://doi.org/10.1101/2021.02.17.431591
Catherine F Hatton
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Rachel A Botting
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Maria Emilia Dueñas
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Iram J Haq
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
3Paediatric Respiratory Medicine, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
Bernard Verdon
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Benjamin J Thompson
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Jarmila Stremenova Spegarova
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Florian Gothe
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
4Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, Ludwig-Maximilians-Universität Munich, Munich, Germany
Emily Stephenson
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Aaron I Gardner
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Sandra Murphy
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Jonathan Scott
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
James P Garnett
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Sean Carrie
5Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK
Jason Powell
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
C M Anjam Khan
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Lei Huang
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Rafiqul Hussain
6Genomics Core Facility, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Jonathan Coxhead
6Genomics Core Facility, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Tracey Davey
7Electron Microscopy Research Services, Newcastle University, Newcastle upon Tyne, UK
A John Simpson
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Muzlifah Haniffa
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
8NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
9Department of Dermatology, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
10Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK
Sophie Hambleton
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
11Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK
Malcolm Brodlie
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
3Paediatric Respiratory Medicine, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
Chris Ward
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
Matthias Trost
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Gary Reynolds
2Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Christopher J A Duncan
1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
12Department of Infection and Tropical Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, UK
Posted September 09, 2021.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2
Catherine F Hatton, Rachel A Botting, Maria Emilia Dueñas, Iram J Haq, Bernard Verdon, Benjamin J Thompson, Jarmila Stremenova Spegarova, Florian Gothe, Emily Stephenson, Aaron I Gardner, Sandra Murphy, Jonathan Scott, James P Garnett, Sean Carrie, Jason Powell, C M Anjam Khan, Lei Huang, Rafiqul Hussain, Jonathan Coxhead, Tracey Davey, A John Simpson, Muzlifah Haniffa, Sophie Hambleton, Malcolm Brodlie, Chris Ward, Matthias Trost, Gary Reynolds, Christopher J A Duncan
bioRxiv 2021.02.17.431591; doi: https://doi.org/10.1101/2021.02.17.431591
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2
Catherine F Hatton, Rachel A Botting, Maria Emilia Dueñas, Iram J Haq, Bernard Verdon, Benjamin J Thompson, Jarmila Stremenova Spegarova, Florian Gothe, Emily Stephenson, Aaron I Gardner, Sandra Murphy, Jonathan Scott, James P Garnett, Sean Carrie, Jason Powell, C M Anjam Khan, Lei Huang, Rafiqul Hussain, Jonathan Coxhead, Tracey Davey, A John Simpson, Muzlifah Haniffa, Sophie Hambleton, Malcolm Brodlie, Chris Ward, Matthias Trost, Gary Reynolds, Christopher J A Duncan
bioRxiv 2021.02.17.431591; doi: https://doi.org/10.1101/2021.02.17.431591
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