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TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells

Bruno Silva, Rajika Arora, Claus M. Azzalin
doi: https://doi.org/10.1101/2021.02.18.431840
Bruno Silva
1Instituto de Medicina Molecular João Lobo Antunes (iMM), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
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Rajika Arora
1Instituto de Medicina Molecular João Lobo Antunes (iMM), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
2Institute for Molecular Health Sciences, ETHZ, Zürich, Switzerland
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Claus M. Azzalin
1Instituto de Medicina Molecular João Lobo Antunes (iMM), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
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  • For correspondence: cmazzalin@medicina.ulisboa.pt
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Article Information

doi 
https://doi.org/10.1101/2021.02.18.431840
History 
  • February 18, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Bruno Silva1,3,
  2. Rajika Arora1,2,3 and
  3. Claus M. Azzalin1,4,*
  1. 1Instituto de Medicina Molecular João Lobo Antunes (iMM), Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal
  2. 2Institute for Molecular Health Sciences, ETHZ, Zürich, Switzerland
  1. ↵*Correspondence: email cmazzalin{at}medicina.ulisboa.pt
  1. ↵3 These authors contributed equally

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Posted February 18, 2021.
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TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells
Bruno Silva, Rajika Arora, Claus M. Azzalin
bioRxiv 2021.02.18.431840; doi: https://doi.org/10.1101/2021.02.18.431840
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TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells
Bruno Silva, Rajika Arora, Claus M. Azzalin
bioRxiv 2021.02.18.431840; doi: https://doi.org/10.1101/2021.02.18.431840

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