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Unique functions for Notch4 in murine embryonic lymphangiogenesis

Ajit Muley, Minji Kim Uh, Jennifer M. James, Aino Murtomaki, Joseph D. McCarron, Chris Kitajewski, Maria Gnarra, Gloria Riitano, Yoh-suke Mukouyama, Jan Kitajewski, View ORCID ProfileCarrie J. Shawber
doi: https://doi.org/10.1101/2021.02.19.431982
Ajit Muley
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
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Minji Kim Uh
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
2Department of Pharmacology, Columbia University Medical Center, New York, NY 10032, USA
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Jennifer M. James
3Laboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
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Aino Murtomaki
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
4Wihuri Research Institute, Biomedicum Helsinki, Haartmaninkatu, Helsinki, 8,00290 Finland
5Translational Cancer Medicine Program, Faculty of Medicine and Helsinki Institute of Life Science, University of Helsinki, Helsinki,, FI-00014, Finland
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Joseph D. McCarron
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
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Chris Kitajewski
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
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Maria Gnarra
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
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Gloria Riitano
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
6Departments of Molecular Medicine and Experimental Medicine, Sapienza University, Rome, 00185, Italy
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Yoh-suke Mukouyama
3Laboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
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Jan Kitajewski
7Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL 60612, USA
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Carrie J. Shawber
1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
8Department of Surgery, Columbia University Medical Center, New York, NY 10032, USA
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  • ORCID record for Carrie J. Shawber
  • For correspondence: cjs2002@cumc.columbia.edu
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Article Information

doi 
https://doi.org/10.1101/2021.02.19.431982
History 
  • February 20, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Ajit Muley1,*,
  2. Minji Kim Uh1,2,*,
  3. Jennifer M. James3,
  4. Aino Murtomaki1,4,5,
  5. Joseph D. McCarron1,
  6. Chris Kitajewski1,
  7. Maria Gnarra1,
  8. Gloria Riitano1,6,
  9. Yoh-suke Mukouyama3,
  10. Jan Kitajewski7 and
  11. Carrie J. Shawber1,8,#
  1. 1Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY 10032, USA
  2. 2Department of Pharmacology, Columbia University Medical Center, New York, NY 10032, USA
  3. 3Laboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA
  4. 4Wihuri Research Institute, Biomedicum Helsinki, Haartmaninkatu, Helsinki, 8,00290 Finland
  5. 5Translational Cancer Medicine Program, Faculty of Medicine and Helsinki Institute of Life Science, University of Helsinki, Helsinki,, FI-00014, Finland
  6. 6Departments of Molecular Medicine and Experimental Medicine, Sapienza University, Rome, 00185, Italy
  7. 7Department of Physiology and Biophysics, University of Illinois Chicago, Chicago, IL 60612, USA
  8. 8Department of Surgery, Columbia University Medical Center, New York, NY 10032, USA
  1. ↵#Corresponding Author:
    Carrie J. Shawber, Columbia University Medical Center, Physician and Surgeons, 16-440B, 630 W. 168th St., New York, NY 10032, (212) 305-7617, cjs2002{at}cumc.columbia.edu
  1. ↵* These first authors contributed equally to this work

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Unique functions for Notch4 in murine embryonic lymphangiogenesis
Ajit Muley, Minji Kim Uh, Jennifer M. James, Aino Murtomaki, Joseph D. McCarron, Chris Kitajewski, Maria Gnarra, Gloria Riitano, Yoh-suke Mukouyama, Jan Kitajewski, Carrie J. Shawber
bioRxiv 2021.02.19.431982; doi: https://doi.org/10.1101/2021.02.19.431982
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Unique functions for Notch4 in murine embryonic lymphangiogenesis
Ajit Muley, Minji Kim Uh, Jennifer M. James, Aino Murtomaki, Joseph D. McCarron, Chris Kitajewski, Maria Gnarra, Gloria Riitano, Yoh-suke Mukouyama, Jan Kitajewski, Carrie J. Shawber
bioRxiv 2021.02.19.431982; doi: https://doi.org/10.1101/2021.02.19.431982

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