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Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells

Emi Sano, Ayaka Sakamoto, Natsumi Mimura, Ai Hirabayashi, Yukiko Muramoto, Takeshi Noda, Takuya Yamamoto, Kazuo Takayama
doi: https://doi.org/10.1101/2021.02.22.432218
Emi Sano
1Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan
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Ayaka Sakamoto
1Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan
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Natsumi Mimura
1Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan
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Ai Hirabayashi
2Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
3CREST, Japan Science and Technology Agency (JST), Kawaguchi 332-0012, Japan
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Yukiko Muramoto
2Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
3CREST, Japan Science and Technology Agency (JST), Kawaguchi 332-0012, Japan
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Takeshi Noda
2Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan
3CREST, Japan Science and Technology Agency (JST), Kawaguchi 332-0012, Japan
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Takuya Yamamoto
1Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan
4Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto 606-8501 Japan
5Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), Kyoto 606-8507, Japan
6AMED-CREST, Japan Agency for Medical Research and Development (AMED), Tokyo 100-0004, Japan
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Kazuo Takayama
1Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan
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  • For correspondence: kazuo.takayama@cira.kyoto-u.ac.jp
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Posted February 22, 2021.
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Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells
Emi Sano, Ayaka Sakamoto, Natsumi Mimura, Ai Hirabayashi, Yukiko Muramoto, Takeshi Noda, Takuya Yamamoto, Kazuo Takayama
bioRxiv 2021.02.22.432218; doi: https://doi.org/10.1101/2021.02.22.432218
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Modeling SARS-CoV-2 infection and its individual differences with ACE2-expressing human iPS cells
Emi Sano, Ayaka Sakamoto, Natsumi Mimura, Ai Hirabayashi, Yukiko Muramoto, Takeshi Noda, Takuya Yamamoto, Kazuo Takayama
bioRxiv 2021.02.22.432218; doi: https://doi.org/10.1101/2021.02.22.432218

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