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Acute and chronic effects of exams week on cortisol production in undergraduate students

View ORCID ProfileFilipy Borghi, Priscila Cristina da Silva, View ORCID ProfileFernando Canova, Aglecio Luiz Souza, Aline Barbedo Arouca, View ORCID ProfileDora Maria Grassi-Kassisse
doi: https://doi.org/10.1101/2021.02.23.432585
Filipy Borghi
1LABEEST - Laboratory of Stress Study, Department of Structural and Functional Biology. Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil
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Priscila Cristina da Silva
1LABEEST - Laboratory of Stress Study, Department of Structural and Functional Biology. Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil
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Fernando Canova
1LABEEST - Laboratory of Stress Study, Department of Structural and Functional Biology. Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil
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Aglecio Luiz Souza
2Unidade Metabólica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), São Paulo, Brazil
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Aline Barbedo Arouca
1LABEEST - Laboratory of Stress Study, Department of Structural and Functional Biology. Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil
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Dora Maria Grassi-Kassisse
1LABEEST - Laboratory of Stress Study, Department of Structural and Functional Biology. Institute of Biology, University of Campinas – UNICAMP, Campinas, São Paulo, Brazil
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ABSTRACT

Undergraduate students experience many levels of stress throughout their university trajectory. The pressure to achieve good results highlight the exams week in the Universities as a stimulus that triggers psychosocial stress and increased release of cortisol. Considering the increasingly experience an undue amount of stress, we aimed in this study to investigate the short- and long-term effects of exams week on HPA axis in undergraduates by the cortisol production. Twenty-eight undergraduates aged 18-24 years from biological sciences during the final exams’ week at the end of the school year collected hair and saliva for cortisol measures. Hair cortisol was significantly higher in exams month. They exhibited cortisol rhythmicity and preserved CAR (cortisol awakening response) even under psychosocial stress. The exams week is a trigger for psychosocial stress, however, did not generate significant short-term changes in cortisol rhythmicity. Thus, it is evident that young people adapt to the stressful stimulus, avoiding a possible trigger for mental illness.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
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Posted February 24, 2021.
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Acute and chronic effects of exams week on cortisol production in undergraduate students
Filipy Borghi, Priscila Cristina da Silva, Fernando Canova, Aglecio Luiz Souza, Aline Barbedo Arouca, Dora Maria Grassi-Kassisse
bioRxiv 2021.02.23.432585; doi: https://doi.org/10.1101/2021.02.23.432585
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Acute and chronic effects of exams week on cortisol production in undergraduate students
Filipy Borghi, Priscila Cristina da Silva, Fernando Canova, Aglecio Luiz Souza, Aline Barbedo Arouca, Dora Maria Grassi-Kassisse
bioRxiv 2021.02.23.432585; doi: https://doi.org/10.1101/2021.02.23.432585

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