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Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons
View ORCID ProfileMichael S. Breen, Tom Rusielewicz, Heather N. Bader, Carina Seah, Changxin Xu, Christopher J. Hunter, Barry McCarthy, Mitali Chattopadhyay, Frank Desarnaud, Iouri Makotkine, Janine D. Flory, Linda M. Bierer, Migle Staniskyte, NYSCF Global Array Team, Scott A. Noggle, View ORCID ProfileDaniel Paull, Kristen J. Brennand, Rachel Yehuda
doi: https://doi.org/10.1101/2021.03.01.433391
Michael S. Breen
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
2Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
3Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
Tom Rusielewicz
4The New York Stem Cell Foundation Research Institute, New York, New York, 10019 USA
Heather N. Bader
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Carina Seah
3Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
6Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
7Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
8Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029
Changxin Xu
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Christopher J. Hunter
4The New York Stem Cell Foundation Research Institute, New York, New York, 10019 USA
Barry McCarthy
4The New York Stem Cell Foundation Research Institute, New York, New York, 10019 USA
Mitali Chattopadhyay
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Frank Desarnaud
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Iouri Makotkine
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Janine D. Flory
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Linda M. Bierer
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Migle Staniskyte
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
4The New York Stem Cell Foundation Research Institute, New York, New York, 10019 USA
Scott A. Noggle
4The New York Stem Cell Foundation Research Institute, New York, New York, 10019 USA
Daniel Paull
4The New York Stem Cell Foundation Research Institute, New York, New York, 10019 USA
Kristen J. Brennand
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
2Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
3Pamela Sklar Division of Psychiatric Genomics, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
6Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
7Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
8Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029
9Department of Psychiatry, Yale University School of Medicine, New Haven CT 06511
Rachel Yehuda
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, 10029 USA
5James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA
Article usage
Posted March 02, 2021.
Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons
Michael S. Breen, Tom Rusielewicz, Heather N. Bader, Carina Seah, Changxin Xu, Christopher J. Hunter, Barry McCarthy, Mitali Chattopadhyay, Frank Desarnaud, Iouri Makotkine, Janine D. Flory, Linda M. Bierer, Migle Staniskyte, NYSCF Global Array Team, Scott A. Noggle, Daniel Paull, Kristen J. Brennand, Rachel Yehuda
bioRxiv 2021.03.01.433391; doi: https://doi.org/10.1101/2021.03.01.433391
Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons
Michael S. Breen, Tom Rusielewicz, Heather N. Bader, Carina Seah, Changxin Xu, Christopher J. Hunter, Barry McCarthy, Mitali Chattopadhyay, Frank Desarnaud, Iouri Makotkine, Janine D. Flory, Linda M. Bierer, Migle Staniskyte, NYSCF Global Array Team, Scott A. Noggle, Daniel Paull, Kristen J. Brennand, Rachel Yehuda
bioRxiv 2021.03.01.433391; doi: https://doi.org/10.1101/2021.03.01.433391
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