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TRAIT2D: a Software for Quantitative Analysis of Single Particle Diffusion Data

View ORCID ProfileFrancesco Reina, John M. A. Wigg, Mariia Dmitrieva, Joёl Lefebvre, Jens Rittscher, Christian Eggeling
doi: https://doi.org/10.1101/2021.03.04.433888
Francesco Reina
1Leibniz-Institüt für Photonische Technologien e.V., Jena, Germany
2Institute of Applied Optics and Biophysics, Friedrich Schiller Universität, Jena, Germany
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  • ORCID record for Francesco Reina
  • For correspondence: francesco.reina@uni-jena.de
John M. A. Wigg
2Institute of Applied Optics and Biophysics, Friedrich Schiller Universität, Jena, Germany
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Mariia Dmitrieva
3Department of Engineering Science, University of Oxford, Oxford, UK
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Joёl Lefebvre
4Département d’informatique, Université du Québec à Montréal, Québec, Canada
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Jens Rittscher
3Department of Engineering Science, University of Oxford, Oxford, UK
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Christian Eggeling
1Leibniz-Institüt für Photonische Technologien e.V., Jena, Germany
2Institute of Applied Optics and Biophysics, Friedrich Schiller Universität, Jena, Germany
5MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, UK
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Summary

Single Particle Tracking (SPT) is one of the most widespread techniques to evaluate particle mobility in a variety of situations, such as in cellular and model membrane dynamics. The proposed TRAIT2D Python library is developed to provide object tracking, trajectory analysis and produce simulated datasets with graphical user interface. The tool allows advanced users to customise the analysis to their requirements.

Availability and implementation: the software has been coded in Python, and can be accessed from: https://github.com/Eggeling-Lab-Microscope-Software/TRAIT2D, or the pypi and condaforge repositories.

A comprehensive user guide is provided at https://eggeling-lab-microscope-software.github.io/TRAIT2D/.

Competing Interest Statement

The authors have declared no competing interest.

Footnotes

  • https://github.com/Eggeling-Lab-Microscope-Software/TRAIT2D

  • https://eggeling-lab-microscope-software.github.io/TRAIT2D/

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted March 05, 2021.
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TRAIT2D: a Software for Quantitative Analysis of Single Particle Diffusion Data
Francesco Reina, John M. A. Wigg, Mariia Dmitrieva, Joёl Lefebvre, Jens Rittscher, Christian Eggeling
bioRxiv 2021.03.04.433888; doi: https://doi.org/10.1101/2021.03.04.433888
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TRAIT2D: a Software for Quantitative Analysis of Single Particle Diffusion Data
Francesco Reina, John M. A. Wigg, Mariia Dmitrieva, Joёl Lefebvre, Jens Rittscher, Christian Eggeling
bioRxiv 2021.03.04.433888; doi: https://doi.org/10.1101/2021.03.04.433888

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