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Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies
Frauke Muecksch, Yiska Weisblum, Christopher O. Barnes, Fabian Schmidt, Dennis Schaefer-Babajew, Julio C C Lorenzi, Andrew I Flyak, Andrew T DeLaitsch, Kathryn E Huey-Tubman, Shurong Hou, Celia A. Schiffer, Christian Gaebler, Zijun Wang, Justin Da Silva, Daniel Poston, Shlomo Finkin, Alice Cho, Melissa Cipolla, Thiago Y. Oliveira, Katrina G. Millard, Victor Ramos, Anna Gazumyan, Magdalena Rutkowska, Marina Caskey, Michel C. Nussenzweig, Pamela J. Bjorkman, Theodora Hatziioannou, Paul D. Bieniasz
doi: https://doi.org/10.1101/2021.03.07.434227
Frauke Muecksch
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Yiska Weisblum
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Christopher O. Barnes
2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
Fabian Schmidt
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Dennis Schaefer-Babajew
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Julio C C Lorenzi
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Andrew I Flyak
2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
Andrew T DeLaitsch
2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
Kathryn E Huey-Tubman
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Shurong Hou
4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655, USA
Celia A. Schiffer
4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655, USA
Christian Gaebler
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Zijun Wang
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Justin Da Silva
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Daniel Poston
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Shlomo Finkin
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Alice Cho
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Melissa Cipolla
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Thiago Y. Oliveira
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Katrina G. Millard
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Victor Ramos
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Anna Gazumyan
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Magdalena Rutkowska
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Marina Caskey
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
Michel C. Nussenzweig
3Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.
4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655, USA
Pamela J. Bjorkman
2Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.
Theodora Hatziioannou
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
Paul D. Bieniasz
1Laboratory of Retrovirology, The Rockefeller University, New York, NY 10065, USA.
4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655, USA
Article usage
Posted March 08, 2021.
Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies
Frauke Muecksch, Yiska Weisblum, Christopher O. Barnes, Fabian Schmidt, Dennis Schaefer-Babajew, Julio C C Lorenzi, Andrew I Flyak, Andrew T DeLaitsch, Kathryn E Huey-Tubman, Shurong Hou, Celia A. Schiffer, Christian Gaebler, Zijun Wang, Justin Da Silva, Daniel Poston, Shlomo Finkin, Alice Cho, Melissa Cipolla, Thiago Y. Oliveira, Katrina G. Millard, Victor Ramos, Anna Gazumyan, Magdalena Rutkowska, Marina Caskey, Michel C. Nussenzweig, Pamela J. Bjorkman, Theodora Hatziioannou, Paul D. Bieniasz
bioRxiv 2021.03.07.434227; doi: https://doi.org/10.1101/2021.03.07.434227
Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies
Frauke Muecksch, Yiska Weisblum, Christopher O. Barnes, Fabian Schmidt, Dennis Schaefer-Babajew, Julio C C Lorenzi, Andrew I Flyak, Andrew T DeLaitsch, Kathryn E Huey-Tubman, Shurong Hou, Celia A. Schiffer, Christian Gaebler, Zijun Wang, Justin Da Silva, Daniel Poston, Shlomo Finkin, Alice Cho, Melissa Cipolla, Thiago Y. Oliveira, Katrina G. Millard, Victor Ramos, Anna Gazumyan, Magdalena Rutkowska, Marina Caskey, Michel C. Nussenzweig, Pamela J. Bjorkman, Theodora Hatziioannou, Paul D. Bieniasz
bioRxiv 2021.03.07.434227; doi: https://doi.org/10.1101/2021.03.07.434227
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