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A metal ion orients mRNA to ensure accurate 2’-O ribosyl methylation of the first nucleotide of the SARS-CoV-2 genome
Thiruselvam Viswanathan, Anurag Misra, Siu-Hong Chan, Shan Qi, Nan Dai, Shailee Arya, Luis Martinez-Sobrido, View ORCID ProfileYogesh K. Gupta
doi: https://doi.org/10.1101/2021.03.12.435174
Thiruselvam Viswanathan
1Greehey Children’s Cancer Research Institute, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
2Department of Biochemistry and Structural Biology, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
Anurag Misra
1Greehey Children’s Cancer Research Institute, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
2Department of Biochemistry and Structural Biology, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
Siu-Hong Chan
3New England Biolabs, 240 County Road, Ipswich, MA, 01938, USA
Shan Qi
1Greehey Children’s Cancer Research Institute, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
2Department of Biochemistry and Structural Biology, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
Nan Dai
3New England Biolabs, 240 County Road, Ipswich, MA, 01938, USA
Shailee Arya
1Greehey Children’s Cancer Research Institute, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
Luis Martinez-Sobrido
4Texas Biomedical Research Institute, San Antonio, TX, 78227, USA
Yogesh K. Gupta
1Greehey Children’s Cancer Research Institute, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
2Department of Biochemistry and Structural Biology, University of Texas Health at San Antonio, 8403 Floyd Curl Drive, San Antonio, TX 78229, USA
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Posted March 12, 2021.
A metal ion orients mRNA to ensure accurate 2’-O ribosyl methylation of the first nucleotide of the SARS-CoV-2 genome
Thiruselvam Viswanathan, Anurag Misra, Siu-Hong Chan, Shan Qi, Nan Dai, Shailee Arya, Luis Martinez-Sobrido, Yogesh K. Gupta
bioRxiv 2021.03.12.435174; doi: https://doi.org/10.1101/2021.03.12.435174
A metal ion orients mRNA to ensure accurate 2’-O ribosyl methylation of the first nucleotide of the SARS-CoV-2 genome
Thiruselvam Viswanathan, Anurag Misra, Siu-Hong Chan, Shan Qi, Nan Dai, Shailee Arya, Luis Martinez-Sobrido, Yogesh K. Gupta
bioRxiv 2021.03.12.435174; doi: https://doi.org/10.1101/2021.03.12.435174
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