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DNA replication during acute MEK inhibition drives acquisition of resistance through amplification of the BRAF oncogene
View ORCID ProfilePrasanna Channathodiyil, View ORCID ProfileAnne Segonds-Pichon, Paul D. Smith, View ORCID ProfileSimon J. Cook, View ORCID ProfileJonathan Houseley
doi: https://doi.org/10.1101/2021.03.23.436572
Prasanna Channathodiyil
1Epigenetics Programme, Babraham Institute, Cambridge, UK
Anne Segonds-Pichon
3Babraham Bioinformatics, Babraham Institute, Cambridge, UK
Paul D. Smith
4Oncology R&D, AstraZeneca CRUK Cambridge Institute, Cambridge, UK
Simon J. Cook
5Signalling programme, Babraham Institute, Cambridge, UK
Jonathan Houseley
1Epigenetics Programme, Babraham Institute, Cambridge, UK
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Posted March 23, 2021.
DNA replication during acute MEK inhibition drives acquisition of resistance through amplification of the BRAF oncogene
Prasanna Channathodiyil, Anne Segonds-Pichon, Paul D. Smith, Simon J. Cook, Jonathan Houseley
bioRxiv 2021.03.23.436572; doi: https://doi.org/10.1101/2021.03.23.436572
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