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Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
View ORCID ProfileKathrin Leppek, View ORCID ProfileGun Woo Byeon, Wipapat Kladwang, View ORCID ProfileHannah K. Wayment-Steele, View ORCID ProfileCraig H. Kerr, View ORCID ProfileAdele F. Xu, View ORCID ProfileDo Soon Kim, View ORCID ProfileVed V. Topkar, Christian Choe, View ORCID ProfileDaphna Rothschild, View ORCID ProfileGerald C. Tiu, View ORCID ProfileRoger Wellington-Oguri, View ORCID ProfileKotaro Fujii, View ORCID ProfileEesha Sharma, View ORCID ProfileAndrew M. Watkins, John J. Nicol, Jonathan Romano, Bojan Tunguz, Eterna Participants, View ORCID ProfileMaria Barna, View ORCID ProfileRhiju Das
doi: https://doi.org/10.1101/2021.03.29.437587
Kathrin Leppek
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Gun Woo Byeon
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Wipapat Kladwang
2Department of Biochemistry, Stanford University, California 94305, USA
Hannah K. Wayment-Steele
3Department of Chemistry, Stanford University, Stanford, California 94305, USA
Craig H. Kerr
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Adele F. Xu
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Do Soon Kim
2Department of Biochemistry, Stanford University, California 94305, USA
Ved V. Topkar
4Program in Biophysics, Stanford University, Stanford, California 94305, USA
Christian Choe
5Department of Bioengineering, Stanford University, Stanford, California 94305, USA
Daphna Rothschild
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Gerald C. Tiu
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Roger Wellington-Oguri
6Eterna Massive Open Laboratory
Kotaro Fujii
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Eesha Sharma
2Department of Biochemistry, Stanford University, California 94305, USA
Andrew M. Watkins
2Department of Biochemistry, Stanford University, California 94305, USA
John J. Nicol
6Eterna Massive Open Laboratory
Jonathan Romano
6Eterna Massive Open Laboratory
7Department of Computer Science and Engineering, State University of New York at Buffalo, Buffalo, New York, 14260, USA
Bojan Tunguz
2Department of Biochemistry, Stanford University, California 94305, USA
Eterna Participants
6Eterna Massive Open Laboratory
Maria Barna
1Department of Genetics, Stanford University, Stanford, California 94305, USA
Rhiju Das
2Department of Biochemistry, Stanford University, California 94305, USA
Article usage
Posted March 30, 2021.
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang, Hannah K. Wayment-Steele, Craig H. Kerr, Adele F. Xu, Do Soon Kim, Ved V. Topkar, Christian Choe, Daphna Rothschild, Gerald C. Tiu, Roger Wellington-Oguri, Kotaro Fujii, Eesha Sharma, Andrew M. Watkins, John J. Nicol, Jonathan Romano, Bojan Tunguz, Eterna Participants, Maria Barna, Rhiju Das
bioRxiv 2021.03.29.437587; doi: https://doi.org/10.1101/2021.03.29.437587
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics
Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang, Hannah K. Wayment-Steele, Craig H. Kerr, Adele F. Xu, Do Soon Kim, Ved V. Topkar, Christian Choe, Daphna Rothschild, Gerald C. Tiu, Roger Wellington-Oguri, Kotaro Fujii, Eesha Sharma, Andrew M. Watkins, John J. Nicol, Jonathan Romano, Bojan Tunguz, Eterna Participants, Maria Barna, Rhiju Das
bioRxiv 2021.03.29.437587; doi: https://doi.org/10.1101/2021.03.29.437587
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