Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2

Emily C. Gale; Abigail E. Powell; Gillie A. Roth; Ben S. Ou; Emily L. Meany; Abigail K. Grosskopf; Julia Adamska; Vittoria C. T. M. Picece; Andrea I. d’Aquino; Bali Pulendran; Peter S. Kim; Eric A. Appel

doi:10.1101/2021.03.31.437792

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Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2

Emily C. Gale, Abigail E. Powell, Gillie A. Roth, Ben S. Ou, Emily L. Meany, Abigail K. Grosskopf, Julia Adamska, Vittoria C. T. M. Picece, Andrea I. d’Aquino, Bali Pulendran, Peter S. Kim, View ORCID ProfileEric A. Appel

doi: https://doi.org/10.1101/2021.03.31.437792

Emily C. Gale

1Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA

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Abigail E. Powell

1Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA

2Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA

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Gillie A. Roth

3Department of Bioengineering, Stanford University, Stanford, CA 94305, USA

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Ben S. Ou

3Department of Bioengineering, Stanford University, Stanford, CA 94305, USA

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Emily L. Meany

3Department of Bioengineering, Stanford University, Stanford, CA 94305, USA

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Abigail K. Grosskopf

5Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA

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Julia Adamska

7Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA

8Institute for Immunity, Transplantation, & Infection, Stanford University School of Medicine, Stanford, CA 94305, USA

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Vittoria C. T. M. Picece

4Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA

6Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich 8093, Switzerland

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Andrea I. d’Aquino

4Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA

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Bali Pulendran

2Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA

7Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA

8Institute for Immunity, Transplantation, & Infection, Stanford University School of Medicine, Stanford, CA 94305, USA

9Department of Pathology, Stanford University School of Medicine. Stanford, CA 94306, USA

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Peter S. Kim

1Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA

2Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA

10Chan Zuckerberg Biohub, San Francisco, CA 94158, USA

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Eric A. Appel

2Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA

3Department of Bioengineering, Stanford University, Stanford, CA 94305, USA

4Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA

8Institute for Immunity, Transplantation, & Infection, Stanford University School of Medicine, Stanford, CA 94305, USA

11Department of Pediatrics - Endocrinology, Stanford University School of Medicine, Stanford, CA 94305, USA

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ORCID record for Eric A. Appel
For correspondence: eappel@stanford.edu

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Posted April 01, 2021.

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Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2

bioRxiv 2021.03.31.437792; doi: https://doi.org/10.1101/2021.03.31.437792

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Hydrogel-based slow release of a receptor-binding domain subunit vaccine elicits neutralizing antibody responses against SARS-CoV-2

bioRxiv 2021.03.31.437792; doi: https://doi.org/10.1101/2021.03.31.437792

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