Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk

View ORCID ProfileSamuel K. Powell, View ORCID ProfileCallan O’Shea, View ORCID ProfileKayla Townsley, View ORCID ProfileIya Prytkova, View ORCID ProfileKristina Dobrindt, Rahat Elahi, Marina Iskhakova, Tova Lambert, Aditi Valada, View ORCID ProfileWill Liao, Seok-Man Ho, Paul A. Slesinger, View ORCID ProfileLaura M. Huckins, Schahram Akbarian, View ORCID ProfileKristen J. Brennand
doi: https://doi.org/10.1101/2021.04.01.438094
Samuel K. Powell
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
4Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
5Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029
6Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven CT, 06511
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Samuel K. Powell
Callan O’Shea
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
4Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
6Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven CT, 06511
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Callan O’Shea
Kayla Townsley
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
4Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
5Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Kayla Townsley
Iya Prytkova
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
5Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Iya Prytkova
Kristina Dobrindt
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
4Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
6Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven CT, 06511
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Kristina Dobrindt
Rahat Elahi
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
4Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marina Iskhakova
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tova Lambert
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Aditi Valada
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Will Liao
7New York Genome Center, New York, NY, 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Will Liao
Seok-Man Ho
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
4Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paul A. Slesinger
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Laura M. Huckins
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Laura M. Huckins
Schahram Akbarian
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: kristen.brennand@mssm.edu schahram.akbarian@mssm.edu
Kristen J. Brennand
1Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029
2Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
3Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029
4Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029
6Division of Molecular Psychiatry, Department of Psychiatry, Yale University, New Haven CT, 06511
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Kristen J. Brennand
  • For correspondence: kristen.brennand@mssm.edu schahram.akbarian@mssm.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading
  • Supplementary Figure 1[supplements/438094_file08.pdf]
  • Supplementary Figure 2[supplements/438094_file09.pdf]
  • Supplementary Figure 3[supplements/438094_file10.pdf]
  • Supplementary Figure 4[supplements/438094_file11.pdf]
  • Supplementary Figure 5[supplements/438094_file12.pdf]
  • Supplementary Figure 6[supplements/438094_file13.pdf]
  • Supplementary Figure 7[supplements/438094_file14.pdf]
  • Supplementary Figure 8[supplements/438094_file15.pdf]
  • Supplementary Figure 9[supplements/438094_file16.pdf]
  • Supplementary Figure 10[supplements/438094_file17.pdf]
  • Supplementary Figure 11[supplements/438094_file18.pdf]
  • Supplementary Figure 12[supplements/438094_file19.pdf]
  • Supplementary Figure 13[supplements/438094_file20.pdf]
  • Supplementary Figure 14[supplements/438094_file21.pdf]
  • Supplementary Figure 15[supplements/438094_file22.pdf]
  • Supplementary Table 1[supplements/438094_file23.txt]
  • Supplementary Table 1[supplements/438094_file24.txt]
  • Supplementary Table 2[supplements/438094_file25.txt]
  • Supplementary Table 3[supplements/438094_file26.txt]
  • Supplementary Table 4[supplements/438094_file27.txt]
  • Supplementary Table 5[supplements/438094_file28.txt]
  • Supplementary Table 5[supplements/438094_file29.txt]
  • Supplementary Table 5[supplements/438094_file30.txt]
  • Supplementary Table 6[supplements/438094_file31.txt]
  • Supplementary Table 7[supplements/438094_file32.txt]
  • Supplementary Table 8[supplements/438094_file33.txt]
  • Supplementary Table 8[supplements/438094_file34.txt]
  • Supplementary Table 9[supplements/438094_file35.txt]
  • Supplementary Table 9[supplements/438094_file36.txt]
  • Supplementary Table 9[supplements/438094_file37.txt]
  • Supplementary Table 10[supplements/438094_file38.txt]
  • Supplementary Table 10[supplements/438094_file39.txt]
  • Supplementary Table 10[supplements/438094_file40.txt]
  • Supplementary Table 10[supplements/438094_file41.txt]
  • Supplementary Table 10[supplements/438094_file42.txt]
  • Supplementary Table 10[supplements/438094_file43.txt]
  • Supplementary Table 11[supplements/438094_file44.txt]
  • Supplementary Table 11[supplements/438094_file45.txt]
  • Supplementary Table 11[supplements/438094_file46.txt]
  • Supplementary Table 11[supplements/438094_file47.txt]
  • Supplementary Table 11[supplements/438094_file48.txt]
  • Supplementary Table 11[supplements/438094_file49.txt]
  • Supplementary Table 11[supplements/438094_file50.txt]
  • Supplementary Table 11[supplements/438094_file51.txt]
  • Supplementary Table 11[supplements/438094_file52.txt]
  • Supplementary Table 12[supplements/438094_file53.txt]
  • Supplementary Table 12[supplements/438094_file54.txt]
  • Supplementary Table 12[supplements/438094_file55.txt]
  • Supplementary Table 12[supplements/438094_file56.txt]
  • Supplementary Table 12[supplements/438094_file57.txt]
  • Supplementary Table 13[supplements/438094_file58.txt]
  • Supplementary Table 13[supplements/438094_file59.txt]
Back to top
PreviousNext
Posted April 02, 2021.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk
Samuel K. Powell, Callan O’Shea, Kayla Townsley, Iya Prytkova, Kristina Dobrindt, Rahat Elahi, Marina Iskhakova, Tova Lambert, Aditi Valada, Will Liao, Seok-Man Ho, Paul A. Slesinger, Laura M. Huckins, Schahram Akbarian, Kristen J. Brennand
bioRxiv 2021.04.01.438094; doi: https://doi.org/10.1101/2021.04.01.438094
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk
Samuel K. Powell, Callan O’Shea, Kayla Townsley, Iya Prytkova, Kristina Dobrindt, Rahat Elahi, Marina Iskhakova, Tova Lambert, Aditi Valada, Will Liao, Seok-Man Ho, Paul A. Slesinger, Laura M. Huckins, Schahram Akbarian, Kristen J. Brennand
bioRxiv 2021.04.01.438094; doi: https://doi.org/10.1101/2021.04.01.438094

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (3602)
  • Biochemistry (7567)
  • Bioengineering (5522)
  • Bioinformatics (20782)
  • Biophysics (10325)
  • Cancer Biology (7978)
  • Cell Biology (11635)
  • Clinical Trials (138)
  • Developmental Biology (6602)
  • Ecology (10200)
  • Epidemiology (2065)
  • Evolutionary Biology (13611)
  • Genetics (9539)
  • Genomics (12844)
  • Immunology (7919)
  • Microbiology (19538)
  • Molecular Biology (7657)
  • Neuroscience (42081)
  • Paleontology (308)
  • Pathology (1257)
  • Pharmacology and Toxicology (2201)
  • Physiology (3267)
  • Plant Biology (7038)
  • Scientific Communication and Education (1294)
  • Synthetic Biology (1951)
  • Systems Biology (5426)
  • Zoology (1116)