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Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein

Shijian Zhang, Eden P. Go, Haitao Ding, Saumya Anang, John C. Kappes, Heather Desaire, View ORCID ProfileJoseph Sodroski
doi: https://doi.org/10.1101/2021.04.01.438120
Shijian Zhang
1Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Department of Microbiology, Harvard Medical School, Boston, MA 02215, USA
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Eden P. Go
2Department of Chemistry, University of Kansas, Lawrence, KS 66049, USA
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Haitao Ding
3Department of Medicine, University of Alabama at Birmingham, AL 35294, USA
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Saumya Anang
1Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Department of Microbiology, Harvard Medical School, Boston, MA 02215, USA
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John C. Kappes
3Department of Medicine, University of Alabama at Birmingham, AL 35294, USA
4Birmingham Veterans Affairs Medical Center, Research Service, Birmingham, AL 35233, USA
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Heather Desaire
2Department of Chemistry, University of Kansas, Lawrence, KS 66049, USA
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Joseph Sodroski
1Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Department of Microbiology, Harvard Medical School, Boston, MA 02215, USA
5Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02215, USA
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  • ORCID record for Joseph Sodroski
  • For correspondence: joseph_sodroski@dfci.harvard.edu
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Article Information

doi 
https://doi.org/10.1101/2021.04.01.438120
History 
  • April 1, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

  1. Shijian Zhang1,*,
  2. Eden P. Go2,*,
  3. Haitao Ding3,
  4. Saumya Anang1,
  5. John C. Kappes3,4,
  6. Heather Desaire2 and
  7. Joseph Sodroski1,5,**
  1. 1Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Department of Microbiology, Harvard Medical School, Boston, MA 02215, USA
  2. 2Department of Chemistry, University of Kansas, Lawrence, KS 66049, USA
  3. 3Department of Medicine, University of Alabama at Birmingham, AL 35294, USA
  4. 4Birmingham Veterans Affairs Medical Center, Research Service, Birmingham, AL 35233, USA
  5. 5Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02215, USA
  1. ↵**Corresponding author: Joseph G. Sodroski, M.D., Dana-Farber Cancer Institute, 450 Brookline Avenue, CLS 1010, Boston, MA 02215, Phone: 617-632-3371, Fax: 617-632-4338, Email: joseph_sodroski{at}dfci.harvard.edu
  1. ↵* These authors contributed equally to the research reported in this manuscript.

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Posted April 01, 2021.
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Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein
Shijian Zhang, Eden P. Go, Haitao Ding, Saumya Anang, John C. Kappes, Heather Desaire, Joseph Sodroski
bioRxiv 2021.04.01.438120; doi: https://doi.org/10.1101/2021.04.01.438120
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Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein
Shijian Zhang, Eden P. Go, Haitao Ding, Saumya Anang, John C. Kappes, Heather Desaire, Joseph Sodroski
bioRxiv 2021.04.01.438120; doi: https://doi.org/10.1101/2021.04.01.438120

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