Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice

Guozhu Zhang; Andrew Deighan; Anil Raj; Laura Robinson; Hannah J. Donato; Gaven Garland; Mackenzie Leland; Baby Martin-McNulty; Ganesh A. Kolumam; Johannes Riegler; Adam Freund; Kevin M. Wright; Gary Churchill

doi:10.1101/2021.04.02.438251

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Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice

Guozhu Zhang, Andrew Deighan, Anil Raj, Laura Robinson, Hannah J. Donato, Gaven Garland, Mackenzie Leland, Baby Martin-McNulty, Ganesh A. Kolumam, Johannes Riegler, Adam Freund, Kevin M. Wright, Gary Churchill

doi: https://doi.org/10.1101/2021.04.02.438251

Guozhu Zhang

*Calico Life Sciences LLC, South San Francisco, California

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Andrew Deighan

†The Jackson Laboratory, Bar Harbor, Maine

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Anil Raj

*Calico Life Sciences LLC, South San Francisco, California

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Laura Robinson

†The Jackson Laboratory, Bar Harbor, Maine

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Hannah J. Donato

†The Jackson Laboratory, Bar Harbor, Maine

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Gaven Garland

†The Jackson Laboratory, Bar Harbor, Maine

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Mackenzie Leland

†The Jackson Laboratory, Bar Harbor, Maine

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Baby Martin-McNulty

*Calico Life Sciences LLC, South San Francisco, California

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Ganesh A. Kolumam

*Calico Life Sciences LLC, South San Francisco, California

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Johannes Riegler

*Calico Life Sciences LLC, South San Francisco, California

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Adam Freund

*Calico Life Sciences LLC, South San Francisco, California

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Kevin M. Wright

*Calico Life Sciences LLC, South San Francisco, California

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For correspondence: wright@calicolabs.com

Gary Churchill

†The Jackson Laboratory, Bar Harbor, Maine

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For correspondence: gary.churchill@jax.org

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Posted April 03, 2021.

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Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice

bioRxiv 2021.04.02.438251; doi: https://doi.org/10.1101/2021.04.02.438251

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Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice

bioRxiv 2021.04.02.438251; doi: https://doi.org/10.1101/2021.04.02.438251

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