New Results
Ageing impairs the airway epithelium defence response to SARS-CoV-2
View ORCID ProfileAlexander Capraro, Sharon L Wong, View ORCID ProfileAnurag Adhikari, Katelin M Allan, View ORCID ProfileHardip R Patel, Ling Zhong, Mark Raftery, View ORCID ProfileAdam Jaffe, Malinna Yeang, Anupriya Aggarwal, View ORCID ProfileLindsay Wu, View ORCID ProfileElvis Pandzic, View ORCID ProfileRenee M Whan, View ORCID ProfileStuart Turville, View ORCID ProfileOrazio Vittorio, View ORCID ProfileRowena A Bull, View ORCID ProfileNadeem Kaakoush, View ORCID ProfileWilliam D Rawlinson, Nicodemus Tedla, View ORCID ProfileFatemeh Vafaee, View ORCID ProfileShafagh A Waters
doi: https://doi.org/10.1101/2021.04.05.437453
Alexander Capraro
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
2Molecular and Integrative Cystic Fibrosis Research Centre (miCF_RC), UNSW Sydney and Sydney Children’s Hospital, Australia
Sharon L Wong
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
2Molecular and Integrative Cystic Fibrosis Research Centre (miCF_RC), UNSW Sydney and Sydney Children’s Hospital, Australia
Anurag Adhikari
3School of Medical Sciences, Faculty of Medicine, UNSW Sydney, NSW, Australia
4The Kirby Institute, UNSW Sydney, NSW, Australia
5Department of Infection and Immunology, Kathmandu Research Institute for Biological Sciences, Lalitpur, Nepal
Katelin M Allan
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
2Molecular and Integrative Cystic Fibrosis Research Centre (miCF_RC), UNSW Sydney and Sydney Children’s Hospital, Australia
Hardip R Patel
6John Curtin School of Medical Research, Australian National University, ACT, Australia
Ling Zhong
7Bioanalytical Mass Spectrometry Facility, UNSW Sydney, NSW, Australia
Mark Raftery
7Bioanalytical Mass Spectrometry Facility, UNSW Sydney, NSW, Australia
Adam Jaffe
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
2Molecular and Integrative Cystic Fibrosis Research Centre (miCF_RC), UNSW Sydney and Sydney Children’s Hospital, Australia
8Department of Respiratory Medicine, Sydney Children’s Hospital, Sydney, NSW, Australia
Malinna Yeang
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
9Virology Research Laboratory, Prince of Wales Hospital Randwick, Sydney, NSW, Australia
10Serology and Virology Division, NSW Health Pathology, Prince of Wales Hospital Randwick, Sydney, NSW, Australia
Anupriya Aggarwal
4The Kirby Institute, UNSW Sydney, NSW, Australia
Lindsay Wu
3School of Medical Sciences, Faculty of Medicine, UNSW Sydney, NSW, Australia
Elvis Pandzic
11Biomedical Imaging Facility, UNSW Sydney, NSW, Australia
Renee M Whan
11Biomedical Imaging Facility, UNSW Sydney, NSW, Australia
Stuart Turville
4The Kirby Institute, UNSW Sydney, NSW, Australia
Orazio Vittorio
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
12Children’s Cancer Institute, UNSW Sydney, NSW, Australia
Rowena A Bull
3School of Medical Sciences, Faculty of Medicine, UNSW Sydney, NSW, Australia
4The Kirby Institute, UNSW Sydney, NSW, Australia
Nadeem Kaakoush
3School of Medical Sciences, Faculty of Medicine, UNSW Sydney, NSW, Australia
William D Rawlinson
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
9Virology Research Laboratory, Prince of Wales Hospital Randwick, Sydney, NSW, Australia
10Serology and Virology Division, NSW Health Pathology, Prince of Wales Hospital Randwick, Sydney, NSW, Australia
Nicodemus Tedla
3School of Medical Sciences, Faculty of Medicine, UNSW Sydney, NSW, Australia
Fatemeh Vafaee
13School of Biotechnology and Biomolecular Sciences, Faculty of Science, UNSW Sydney, NSW, Australia
Shafagh A Waters
1School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW, Australia
2Molecular and Integrative Cystic Fibrosis Research Centre (miCF_RC), UNSW Sydney and Sydney Children’s Hospital, Australia
8Department of Respiratory Medicine, Sydney Children’s Hospital, Sydney, NSW, Australia
Posted April 06, 2021.
Ageing impairs the airway epithelium defence response to SARS-CoV-2
Alexander Capraro, Sharon L Wong, Anurag Adhikari, Katelin M Allan, Hardip R Patel, Ling Zhong, Mark Raftery, Adam Jaffe, Malinna Yeang, Anupriya Aggarwal, Lindsay Wu, Elvis Pandzic, Renee M Whan, Stuart Turville, Orazio Vittorio, Rowena A Bull, Nadeem Kaakoush, William D Rawlinson, Nicodemus Tedla, Fatemeh Vafaee, Shafagh A Waters
bioRxiv 2021.04.05.437453; doi: https://doi.org/10.1101/2021.04.05.437453
Ageing impairs the airway epithelium defence response to SARS-CoV-2
Alexander Capraro, Sharon L Wong, Anurag Adhikari, Katelin M Allan, Hardip R Patel, Ling Zhong, Mark Raftery, Adam Jaffe, Malinna Yeang, Anupriya Aggarwal, Lindsay Wu, Elvis Pandzic, Renee M Whan, Stuart Turville, Orazio Vittorio, Rowena A Bull, Nadeem Kaakoush, William D Rawlinson, Nicodemus Tedla, Fatemeh Vafaee, Shafagh A Waters
bioRxiv 2021.04.05.437453; doi: https://doi.org/10.1101/2021.04.05.437453
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