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Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase
View ORCID ProfileJingkun Zeng, View ORCID ProfileFlorian Weissmann, View ORCID ProfileAgustina P. Bertolin, View ORCID ProfileViktor Posse, View ORCID ProfileBerta Canal, View ORCID ProfileRachel Ulferts, View ORCID ProfileMary Wu, Ruth Harvey, View ORCID ProfileSaira Hussain, View ORCID ProfileJennifer C. Milligan, View ORCID ProfileChloe Roustan, View ORCID ProfileAnnabel Borg, View ORCID ProfileLaura McCoy, View ORCID ProfileLucy S. Drury, View ORCID ProfileSvend Kjaer, View ORCID ProfileJohn McCauley, View ORCID ProfileMichael Howell, View ORCID ProfileRupert Beale, View ORCID ProfileJohn F.X Diffley
doi: https://doi.org/10.1101/2021.04.07.438808
Jingkun Zeng
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Florian Weissmann
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Agustina P. Bertolin
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Viktor Posse
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Berta Canal
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Rachel Ulferts
2Cell Biology of Infection Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Mary Wu
3High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Ruth Harvey
4World Influenza Centre, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Saira Hussain
4World Influenza Centre, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Jennifer C. Milligan
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Chloe Roustan
5Structural Biology, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Annabel Borg
5Structural Biology, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Laura McCoy
6Division of Infection and Immunity, University College London, WC1E 6BT
Lucy S. Drury
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Svend Kjaer
5Structural Biology, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
John McCauley
4World Influenza Centre, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Michael Howell
3High Throughput Screening, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Rupert Beale
2Cell Biology of Infection Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
John F.X Diffley
1Chromosome Replication Laboratory, The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Article usage
Posted April 08, 2021.
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase
Jingkun Zeng, Florian Weissmann, Agustina P. Bertolin, Viktor Posse, Berta Canal, Rachel Ulferts, Mary Wu, Ruth Harvey, Saira Hussain, Jennifer C. Milligan, Chloe Roustan, Annabel Borg, Laura McCoy, Lucy S. Drury, Svend Kjaer, John McCauley, Michael Howell, Rupert Beale, John F.X Diffley
bioRxiv 2021.04.07.438808; doi: https://doi.org/10.1101/2021.04.07.438808
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase
Jingkun Zeng, Florian Weissmann, Agustina P. Bertolin, Viktor Posse, Berta Canal, Rachel Ulferts, Mary Wu, Ruth Harvey, Saira Hussain, Jennifer C. Milligan, Chloe Roustan, Annabel Borg, Laura McCoy, Lucy S. Drury, Svend Kjaer, John McCauley, Michael Howell, Rupert Beale, John F.X Diffley
bioRxiv 2021.04.07.438808; doi: https://doi.org/10.1101/2021.04.07.438808
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