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Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase
View ORCID ProfileSouradeep Basu, View ORCID ProfileTiffany Mak, View ORCID ProfileRachel Ulferts, View ORCID ProfileMary Wu, View ORCID ProfileTom Deegan, View ORCID ProfileRyo Fujisawa, View ORCID ProfileKang Wei Tan, View ORCID ProfileChew Theng Lim, View ORCID ProfileClovis Basier, View ORCID ProfileBerta Canal, View ORCID ProfileJoseph F. Curran, View ORCID ProfileLucy Drury, View ORCID ProfileAllison W. McClure, View ORCID ProfileEmma L. Roberts, View ORCID ProfileFlorian Weissmann, View ORCID ProfileTheresa U. Zeisner, View ORCID ProfileRupert Beale, View ORCID ProfileVictoria H. Cowling, View ORCID ProfileMichael Howell, View ORCID ProfileKarim Labib, View ORCID ProfileJohn F.X. Diffley
doi: https://doi.org/10.1101/2021.04.07.438810
Souradeep Basu
1Cell Cycle Laboratory
Tiffany Mak
1Cell Cycle Laboratory
Rachel Ulferts
2Cell Biology of Infection Laboratory
Mary Wu
3High Throughput Screening
Tom Deegan
5The MRC Protein Phosphorylation and Ubiquitylation Unit
Ryo Fujisawa
5The MRC Protein Phosphorylation and Ubiquitylation Unit
Kang Wei Tan
4Chromosome Replication Laboratory The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Chew Theng Lim
4Chromosome Replication Laboratory The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Clovis Basier
1Cell Cycle Laboratory
Berta Canal
4Chromosome Replication Laboratory The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Joseph F. Curran
1Cell Cycle Laboratory
Lucy Drury
4Chromosome Replication Laboratory The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Allison W. McClure
4Chromosome Replication Laboratory The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Emma L. Roberts
1Cell Cycle Laboratory
Florian Weissmann
4Chromosome Replication Laboratory The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Theresa U. Zeisner
1Cell Cycle Laboratory
Rupert Beale
2Cell Biology of Infection Laboratory
Victoria H. Cowling
6Centre for Gene Regulation and Expression School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
Michael Howell
3High Throughput Screening
Karim Labib
5The MRC Protein Phosphorylation and Ubiquitylation Unit
John F.X. Diffley
4Chromosome Replication Laboratory The Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Posted April 08, 2021.
Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase
Souradeep Basu, Tiffany Mak, Rachel Ulferts, Mary Wu, Tom Deegan, Ryo Fujisawa, Kang Wei Tan, Chew Theng Lim, Clovis Basier, Berta Canal, Joseph F. Curran, Lucy Drury, Allison W. McClure, Emma L. Roberts, Florian Weissmann, Theresa U. Zeisner, Rupert Beale, Victoria H. Cowling, Michael Howell, Karim Labib, John F.X. Diffley
bioRxiv 2021.04.07.438810; doi: https://doi.org/10.1101/2021.04.07.438810
Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase
Souradeep Basu, Tiffany Mak, Rachel Ulferts, Mary Wu, Tom Deegan, Ryo Fujisawa, Kang Wei Tan, Chew Theng Lim, Clovis Basier, Berta Canal, Joseph F. Curran, Lucy Drury, Allison W. McClure, Emma L. Roberts, Florian Weissmann, Theresa U. Zeisner, Rupert Beale, Victoria H. Cowling, Michael Howell, Karim Labib, John F.X. Diffley
bioRxiv 2021.04.07.438810; doi: https://doi.org/10.1101/2021.04.07.438810
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