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Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease
View ORCID ProfileBerta Canal, View ORCID ProfileAllison W. McClure, View ORCID ProfileJoseph F. Curran, View ORCID ProfileMary Wu, View ORCID ProfileRachel Ulferts, View ORCID ProfileFlorian Weissmann, View ORCID ProfileJingkun Zeng, View ORCID ProfileAgustina P. Bertolin, View ORCID ProfileJennifer C. Milligan, View ORCID ProfileSouradeep Basu, View ORCID ProfileLucy S. Drury, View ORCID ProfileTom Deegan, View ORCID ProfileRyo Fujisawa, View ORCID ProfileEmma L. Roberts, View ORCID ProfileClovis Basier, View ORCID ProfileKarim Labib, View ORCID ProfileRupert Beale, View ORCID ProfileMichael Howell, View ORCID ProfileJohn F.X Diffley
doi: https://doi.org/10.1101/2021.04.07.438812
Berta Canal
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Allison W. McClure
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Joseph F. Curran
2Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Mary Wu
4High Throughput Screening, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Rachel Ulferts
3Cell Biology of Infection Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Florian Weissmann
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Jingkun Zeng
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Agustina P. Bertolin
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Jennifer C. Milligan
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Souradeep Basu
2Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Lucy S. Drury
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Tom Deegan
5The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
Ryo Fujisawa
5The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
Emma L. Roberts
2Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Clovis Basier
2Cell Cycle Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Karim Labib
5The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
Rupert Beale
3Cell Biology of Infection Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Michael Howell
4High Throughput Screening, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
John F.X Diffley
1Chromosome Replication Laboratory, the Francis Crick Institute, 1 Midland Road, London, NW1 1AT
Article usage
Posted April 08, 2021.
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease
Berta Canal, Allison W. McClure, Joseph F. Curran, Mary Wu, Rachel Ulferts, Florian Weissmann, Jingkun Zeng, Agustina P. Bertolin, Jennifer C. Milligan, Souradeep Basu, Lucy S. Drury, Tom Deegan, Ryo Fujisawa, Emma L. Roberts, Clovis Basier, Karim Labib, Rupert Beale, Michael Howell, John F.X Diffley
bioRxiv 2021.04.07.438812; doi: https://doi.org/10.1101/2021.04.07.438812
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease
Berta Canal, Allison W. McClure, Joseph F. Curran, Mary Wu, Rachel Ulferts, Florian Weissmann, Jingkun Zeng, Agustina P. Bertolin, Jennifer C. Milligan, Souradeep Basu, Lucy S. Drury, Tom Deegan, Ryo Fujisawa, Emma L. Roberts, Clovis Basier, Karim Labib, Rupert Beale, Michael Howell, John F.X Diffley
bioRxiv 2021.04.07.438812; doi: https://doi.org/10.1101/2021.04.07.438812
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