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Hematopoietic stem cell requirement for macrophage regeneration is tissue-specific

Devon J. Eddins, Astrid Kosters, Jeffrey Waters, Jasmine Sosa, Megan Phillips, Koshika Yadava, Leonore A. Herzenberg, Hedwich F. Kuipers, View ORCID ProfileEliver Eid Bou Ghosn
doi: https://doi.org/10.1101/2021.04.08.439077
Devon J. Eddins
*Lowance Center for Human Immunology, Department of Medicine, Division of Immunology and Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA
†Department of Pediatrics, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA
‡Emory Vaccine Center, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA
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Astrid Kosters
*Lowance Center for Human Immunology, Department of Medicine, Division of Immunology and Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA
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Jeffrey Waters
§Department of Genetics, Stanford University, Stanford, CA 94305, USA
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Jasmine Sosa
§Department of Genetics, Stanford University, Stanford, CA 94305, USA
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Megan Phillips
§Department of Genetics, Stanford University, Stanford, CA 94305, USA
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Koshika Yadava
¶Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
∥Friedrich Miescher Institute for Biomedical Research (FMI), Maulbeerstrasse 66, 4058 Basel, Switzerland
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Leonore A. Herzenberg
§Department of Genetics, Stanford University, Stanford, CA 94305, USA
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Hedwich F. Kuipers
¶Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
#Departments of Clinical Neurosciences and Cell Biology & Anatomy, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada
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Eliver Eid Bou Ghosn
*Lowance Center for Human Immunology, Department of Medicine, Division of Immunology and Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA
†Department of Pediatrics, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA
‡Emory Vaccine Center, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA
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  • ORCID record for Eliver Eid Bou Ghosn
  • For correspondence: eliver.ghosn@emory.edu
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Article Information

doi 
https://doi.org/10.1101/2021.04.08.439077
History 
  • April 10, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Devon J. Eddins*,†,‡,1,
  2. Astrid Kosters*,1,
  3. Jeffrey Waters§,
  4. Jasmine Sosa§,
  5. Megan Phillips§,
  6. Koshika Yadava¶∥,
  7. Leonore A. Herzenberg§,
  8. Hedwich F. Kuipers¶,# and
  9. Eliver Eid Bou Ghosn*,†,‡,$
  1. *Lowance Center for Human Immunology, Department of Medicine, Division of Immunology and Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA
  2. †Department of Pediatrics, Division of Rheumatology, Emory University School of Medicine, Atlanta, GA 30322, USA
  3. ‡Emory Vaccine Center, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA
  4. §Department of Genetics, Stanford University, Stanford, CA 94305, USA
  5. ¶Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
  6. ∥Friedrich Miescher Institute for Biomedical Research (FMI), Maulbeerstrasse 66, 4058 Basel, Switzerland
  7. #Departments of Clinical Neurosciences and Cell Biology & Anatomy, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada
  1. ↵$Corresponding author contact info
    , Eliver E.B. Ghosn: Lowance Center for Human Immunology, Health Sciences Research Building, 1760 Haygood Dr. NE, E240, Atlanta, GA 30322, USA; tel: +1-404-712-3211; email: eliver.ghosn{at}emory.edu
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Hematopoietic stem cell requirement for macrophage regeneration is tissue-specific
Devon J. Eddins, Astrid Kosters, Jeffrey Waters, Jasmine Sosa, Megan Phillips, Koshika Yadava, Leonore A. Herzenberg, Hedwich F. Kuipers, Eliver Eid Bou Ghosn
bioRxiv 2021.04.08.439077; doi: https://doi.org/10.1101/2021.04.08.439077
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Hematopoietic stem cell requirement for macrophage regeneration is tissue-specific
Devon J. Eddins, Astrid Kosters, Jeffrey Waters, Jasmine Sosa, Megan Phillips, Koshika Yadava, Leonore A. Herzenberg, Hedwich F. Kuipers, Eliver Eid Bou Ghosn
bioRxiv 2021.04.08.439077; doi: https://doi.org/10.1101/2021.04.08.439077

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