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Pre-existing chromatin accessibility and gene expression differences among naïve CD4+ T cells influence effector potential
Dakota Rogers, Aditi Sood, HanChen Wang, Jasper J. P. van Beek, Thomas J. Rademaker, Patricio Artusa, Caitlin Schneider, Connie Shen, Dylan C. Wong, Marie-Ève Lebel, Stephanie A. Condotta, Martin J. Richer, Andrew J. Martins, John S. Tsang, Luis Barreiro, Paul Francois, David Langlais, Heather J. Melichar, View ORCID ProfileJohannes Textor, View ORCID ProfileJudith N. Mandl
doi: https://doi.org/10.1101/2021.04.21.440846
Dakota Rogers
1Department of Physiology, McGill University, Montreal, Canada
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
Aditi Sood
3Immunology-Oncology Unit, Maisonneuve-Rosemont Hospital Research Center, Montreal, Canada
4Department of Microbiology, Immunology, and Infectious Disease, Université de Montréal, Montréal, Canada
HanChen Wang
1Department of Physiology, McGill University, Montreal, Canada
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
Jasper J. P. van Beek
6Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands
Thomas J. Rademaker
7Department of Physics, McGill University, Montreal, Canada
Patricio Artusa
1Department of Physiology, McGill University, Montreal, Canada
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
Caitlin Schneider
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
8Department of Microbiology and Immunology, McGill University, Montreal, Canada
Connie Shen
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
8Department of Microbiology and Immunology, McGill University, Montreal, Canada
Dylan C. Wong
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
8Department of Microbiology and Immunology, McGill University, Montreal, Canada
Marie-Ève Lebel
3Immunology-Oncology Unit, Maisonneuve-Rosemont Hospital Research Center, Montreal, Canada
Stephanie A. Condotta
8Department of Microbiology and Immunology, McGill University, Montreal, Canada
Martin J. Richer
8Department of Microbiology and Immunology, McGill University, Montreal, Canada
Andrew J. Martins
9Systems Genomics and Bioinformatics Unit, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA
John S. Tsang
9Systems Genomics and Bioinformatics Unit, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA
Luis Barreiro
10Department of Genetic Medicine, University of Chicago, Chicago, USA
Paul Francois
7Department of Physics, McGill University, Montreal, Canada
David Langlais
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
11Department of Human Genetics, McGill University, Montreal, Canada
12McGill University Genome Centre, Montreal, QC, Canada
Heather J. Melichar
3Immunology-Oncology Unit, Maisonneuve-Rosemont Hospital Research Center, Montreal, Canada
5Department of Medicine, Université de Montréal, Montréal, Canada
Johannes Textor
6Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands
Judith N. Mandl
1Department of Physiology, McGill University, Montreal, Canada
2McGill Research Centre for Complex Traits, McGill University, Montreal, Canada
8Department of Microbiology and Immunology, McGill University, Montreal, Canada
Article usage
Posted April 22, 2021.
Pre-existing chromatin accessibility and gene expression differences among naïve CD4+ T cells influence effector potential
Dakota Rogers, Aditi Sood, HanChen Wang, Jasper J. P. van Beek, Thomas J. Rademaker, Patricio Artusa, Caitlin Schneider, Connie Shen, Dylan C. Wong, Marie-Ève Lebel, Stephanie A. Condotta, Martin J. Richer, Andrew J. Martins, John S. Tsang, Luis Barreiro, Paul Francois, David Langlais, Heather J. Melichar, Johannes Textor, Judith N. Mandl
bioRxiv 2021.04.21.440846; doi: https://doi.org/10.1101/2021.04.21.440846
Pre-existing chromatin accessibility and gene expression differences among naïve CD4+ T cells influence effector potential
Dakota Rogers, Aditi Sood, HanChen Wang, Jasper J. P. van Beek, Thomas J. Rademaker, Patricio Artusa, Caitlin Schneider, Connie Shen, Dylan C. Wong, Marie-Ève Lebel, Stephanie A. Condotta, Martin J. Richer, Andrew J. Martins, John S. Tsang, Luis Barreiro, Paul Francois, David Langlais, Heather J. Melichar, Johannes Textor, Judith N. Mandl
bioRxiv 2021.04.21.440846; doi: https://doi.org/10.1101/2021.04.21.440846
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