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Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees

Pragya D. Yadav, Gajanan N. Sapkal, Priya Abraham, Raches Ella, Gururaj Deshpande, Deepak Y. Patil, Dimpal A Nyayanit, Nivedita Gupta, Rima R. Sahay, Anita M Shete, Samiran Panda, Balram Bhargava, V. Krishna Mohan
doi: https://doi.org/10.1101/2021.04.23.441101
Pragya D. Yadav
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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  • For correspondence: hellopragya22@gmail.com
Gajanan N. Sapkal
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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Priya Abraham
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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Raches Ella
2Bharat Biotech International Limited, Genome Valley, Hyderabad, Telangana, India Pin-500 078
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Gururaj Deshpande
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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Deepak Y. Patil
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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Dimpal A Nyayanit
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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Nivedita Gupta
3Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
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Rima R. Sahay
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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Anita M Shete
1Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, India, Pin-411021
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Samiran Panda
3Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
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Balram Bhargava
3Indian Council of Medical Research, V. Ramalingaswami Bhawan, P.O. Box No. 4911, Ansari Nagar, New Delhi, India Pin-110029
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V. Krishna Mohan
2Bharat Biotech International Limited, Genome Valley, Hyderabad, Telangana, India Pin-500 078
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Abstract

The drastic rise in the number of cases in Maharashtra, India has created a matter of concern for public health experts. Twelve isolates of VUI lineage B.1.617 were propagated in VeroCCL81 cells and characterized. Convalescent sera of the COVID-19 cases and recipients of BBV152 (Covaxin) were able to neutralize VUI B.1.617.

Competing Interest Statement

The authors have declared no competing interest.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted April 23, 2021.
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Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees
Pragya D. Yadav, Gajanan N. Sapkal, Priya Abraham, Raches Ella, Gururaj Deshpande, Deepak Y. Patil, Dimpal A Nyayanit, Nivedita Gupta, Rima R. Sahay, Anita M Shete, Samiran Panda, Balram Bhargava, V. Krishna Mohan
bioRxiv 2021.04.23.441101; doi: https://doi.org/10.1101/2021.04.23.441101
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Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees
Pragya D. Yadav, Gajanan N. Sapkal, Priya Abraham, Raches Ella, Gururaj Deshpande, Deepak Y. Patil, Dimpal A Nyayanit, Nivedita Gupta, Rima R. Sahay, Anita M Shete, Samiran Panda, Balram Bhargava, V. Krishna Mohan
bioRxiv 2021.04.23.441101; doi: https://doi.org/10.1101/2021.04.23.441101

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