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LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
View ORCID ProfileMarc Emmenegger, Elena De Cecco, View ORCID ProfileMarian Hruska-Plochan, Timo Eninger, View ORCID ProfileMatthias M. Schneider, Melanie Barth, View ORCID ProfileElena Tantardini, Pierre de Rossi, Rebekah G. Langston, Alice Kaganovich, Andrès Gonzalez-Guerra, View ORCID ProfileMerve Avar, View ORCID ProfileDaniel Heinzer, View ORCID ProfileRegina Reimann, Lisa M. Häsler, Therese W. Herling, Naunehal S. Matharu, View ORCID ProfileNatalie Landeck, View ORCID ProfileKelvin Luk, Ronald Melki, Philipp J. Kahle, View ORCID ProfileSimone Hornemann, View ORCID ProfileTuomas P. J. Knowles, View ORCID ProfileMark R. Cookson, Magdalini Polymenidou, View ORCID ProfileMathias Jucker, View ORCID ProfileAdriano Aguzzi
doi: https://doi.org/10.1101/2021.04.25.441302
Marc Emmenegger
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Elena De Cecco
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Marian Hruska-Plochan
2Department of Quantitative Biomedicine, University of Zurich, CH-8057, Switzerland
Timo Eninger
3German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
4Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
Matthias M. Schneider
5Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom
Melanie Barth
3German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
4Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
Elena Tantardini
2Department of Quantitative Biomedicine, University of Zurich, CH-8057, Switzerland
Pierre de Rossi
2Department of Quantitative Biomedicine, University of Zurich, CH-8057, Switzerland
Rebekah G. Langston
6Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Building 35, Room 1A116, 35 Convent Drive, MSC 3707, Bethesda, MD, 20892-3707, USA
Alice Kaganovich
6Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Building 35, Room 1A116, 35 Convent Drive, MSC 3707, Bethesda, MD, 20892-3707, USA
Andrès Gonzalez-Guerra
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Merve Avar
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Daniel Heinzer
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Regina Reimann
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Lisa M. Häsler
3German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
4Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
Therese W. Herling
5Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom
Naunehal S. Matharu
5Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom
Natalie Landeck
6Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Building 35, Room 1A116, 35 Convent Drive, MSC 3707, Bethesda, MD, 20892-3707, USA
Kelvin Luk
7Department of Pathology and Laboratory Medicine and Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA
Ronald Melki
8Institut François Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Fontenay-aux-Roses, France
Philipp J. Kahle
3German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
4Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
Simone Hornemann
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Tuomas P. J. Knowles
5Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom
9Cavendish Laboratory, Department of Physics, University of Cambridge, JJ Thomson Ave, Cambridge CB3 0HE, United Kingdom
Mark R. Cookson
6Cell Biology and Gene Expression Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Building 35, Room 1A116, 35 Convent Drive, MSC 3707, Bethesda, MD, 20892-3707, USA
Magdalini Polymenidou
2Department of Quantitative Biomedicine, University of Zurich, CH-8057, Switzerland
Mathias Jucker
3German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
4Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
Adriano Aguzzi
1Institute of Neuropathology, University of Zurich, CH-8091 Zurich, Switzerland
Article usage
Posted April 26, 2021.
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
Marc Emmenegger, Elena De Cecco, Marian Hruska-Plochan, Timo Eninger, Matthias M. Schneider, Melanie Barth, Elena Tantardini, Pierre de Rossi, Rebekah G. Langston, Alice Kaganovich, Andrès Gonzalez-Guerra, Merve Avar, Daniel Heinzer, Regina Reimann, Lisa M. Häsler, Therese W. Herling, Naunehal S. Matharu, Natalie Landeck, Kelvin Luk, Ronald Melki, Philipp J. Kahle, Simone Hornemann, Tuomas P. J. Knowles, Mark R. Cookson, Magdalini Polymenidou, Mathias Jucker, Adriano Aguzzi
bioRxiv 2021.04.25.441302; doi: https://doi.org/10.1101/2021.04.25.441302
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
Marc Emmenegger, Elena De Cecco, Marian Hruska-Plochan, Timo Eninger, Matthias M. Schneider, Melanie Barth, Elena Tantardini, Pierre de Rossi, Rebekah G. Langston, Alice Kaganovich, Andrès Gonzalez-Guerra, Merve Avar, Daniel Heinzer, Regina Reimann, Lisa M. Häsler, Therese W. Herling, Naunehal S. Matharu, Natalie Landeck, Kelvin Luk, Ronald Melki, Philipp J. Kahle, Simone Hornemann, Tuomas P. J. Knowles, Mark R. Cookson, Magdalini Polymenidou, Mathias Jucker, Adriano Aguzzi
bioRxiv 2021.04.25.441302; doi: https://doi.org/10.1101/2021.04.25.441302
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