Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages

Sebastian Ullrich; Carme Arnan; Carlos Pulido-Quetglas; Ramil Nurtdinov; Alexandre Esteban; Joan Blanco-Fernandez; Estel Aparicio-Prat; Rory Johnson; Sílvia Pérez-Lluch; Roderic Guigó

doi:10.1101/2021.04.26.441397

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Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages

Sebastian Ullrich, View ORCID ProfileCarme Arnan, Carlos Pulido-Quetglas, Ramil Nurtdinov, Alexandre Esteban, Joan Blanco-Fernandez, Estel Aparicio-Prat, Rory Johnson, Sílvia Pérez-Lluch, Roderic Guigó

doi: https://doi.org/10.1101/2021.04.26.441397

Sebastian Ullrich

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

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Carme Arnan

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

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ORCID record for Carme Arnan

Carlos Pulido-Quetglas

4Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Switzerland

5Department for BioMedical Research, University of Bern, Bern, Switzerland

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Ramil Nurtdinov

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

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Alexandre Esteban

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

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Joan Blanco-Fernandez

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

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Estel Aparicio-Prat

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

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Rory Johnson

4Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Switzerland

5Department for BioMedical Research, University of Bern, Bern, Switzerland

6School of Biology and Environmental Science, University College Dublin, Ireland

7Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Ireland

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Sílvia Pérez-Lluch

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

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Roderic Guigó

1Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona (BIST), Catalonia, Spain

2Universitat Pompeu Fabra (UPF), Barcelona, Catalonia, Spain

3Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona, Catalonia, Spain

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For correspondence: roderic.guigo@crg.cat

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Posted April 27, 2021.

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Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages

Sebastian Ullrich, Carme Arnan, Carlos Pulido-Quetglas, Ramil Nurtdinov, Alexandre Esteban, Joan Blanco-Fernandez, Estel Aparicio-Prat, Rory Johnson, Sílvia Pérez-Lluch, Roderic Guigó

bioRxiv 2021.04.26.441397; doi: https://doi.org/10.1101/2021.04.26.441397

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Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages

Sebastian Ullrich, Carme Arnan, Carlos Pulido-Quetglas, Ramil Nurtdinov, Alexandre Esteban, Joan Blanco-Fernandez, Estel Aparicio-Prat, Rory Johnson, Sílvia Pérez-Lluch, Roderic Guigó

bioRxiv 2021.04.26.441397; doi: https://doi.org/10.1101/2021.04.26.441397

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