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Ultraspecific somatic SNV and indel detection in single neurons using primary template-directed amplification
View ORCID ProfileLovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Alon Galor, Michael A. Lodato, View ORCID ProfileCharles Gawad, Jay West, Christopher A. Walsh, Peter J. Park
doi: https://doi.org/10.1101/2021.04.30.442032
Lovelace J. Luquette
1Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
Michael B. Miller
2Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, USA
3Manton Center for Orphan Disease, Boston Children’s Hospital, Boston, MA, USA Departments of Neurology and Pediatrics, Harvard Medical School, Boston, MA, USA and Broad Institute of MIT and Harvard, Cambridge, MA, USA
4Division of Neuropathology, Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
Zinan Zhou
2Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, USA
Craig L. Bohrson
1Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
Alon Galor
1Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
Michael A. Lodato
5Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA
Charles Gawad
6Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA
7Chan Zuckerberg Biohub, San Francisco, CA, USA
Jay West
8BioSkryb, Durham, NC, USA
Christopher A. Walsh
2Division of Genetics and Genomics, Boston Children’s Hospital, Boston, MA, USA
3Manton Center for Orphan Disease, Boston Children’s Hospital, Boston, MA, USA Departments of Neurology and Pediatrics, Harvard Medical School, Boston, MA, USA and Broad Institute of MIT and Harvard, Cambridge, MA, USA
9Howard Hughes Medical Institute, Boston Children’s Hospital, Boston, MA, USA
Peter J. Park
1Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
10Ludwig Center at Harvard, Boston, MA, USA
Article usage
Posted May 01, 2021.
Ultraspecific somatic SNV and indel detection in single neurons using primary template-directed amplification
Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Alon Galor, Michael A. Lodato, Charles Gawad, Jay West, Christopher A. Walsh, Peter J. Park
bioRxiv 2021.04.30.442032; doi: https://doi.org/10.1101/2021.04.30.442032
Ultraspecific somatic SNV and indel detection in single neurons using primary template-directed amplification
Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Alon Galor, Michael A. Lodato, Charles Gawad, Jay West, Christopher A. Walsh, Peter J. Park
bioRxiv 2021.04.30.442032; doi: https://doi.org/10.1101/2021.04.30.442032
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