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The K18-hACE2 Transgenic Mouse Model Recapitulates Non-Severe and Severe COVID-19 in Response to Infectious Dose of SARS-CoV-2 Virus
Wenjuan Dong, Heather Mead, Sierra Jaramillo, Tasha Barr, Daniel S. Kollath, Vanessa K. Coyne, Nathan E. Stone, Ashley Jones, Jianying Zhang, Aimin Li, Li-Shu Wang, Martha Milanes-Yearsley, Paul S Keim, Bridget Marie Barker, Michael Caligiuri, Jianhua Yu
doi: https://doi.org/10.1101/2021.05.08.443244
Wenjuan Dong
aDepartment of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA 91010
bHematologic Malignancies Research Institute, City of Hope National Medical Center, Duarte, CA 91010
Heather Mead
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Sierra Jaramillo
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Tasha Barr
aDepartment of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA 91010
bHematologic Malignancies Research Institute, City of Hope National Medical Center, Duarte, CA 91010
Daniel S. Kollath
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Vanessa K. Coyne
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Nathan E. Stone
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Ashley Jones
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Jianying Zhang
dDepartment of Computational and Quantitative Medicine, City of Hope National Medical Center, Duarte, CA 91010
Aimin Li
ePathology Shared Resource Core, Beckman Research Institute, City of Hope National Medical Center, Los Angeles, CA 91010, USA
Li-Shu Wang
fDivision of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Martha Milanes-Yearsley
gDepartment of Pathology, The Ohio State University, Columbus, OH 43210
Paul S Keim
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Bridget Marie Barker
cPathogen and Microbiome Institute, Northern Arizona University, Flagstaff, AZ 86011
Michael Caligiuri
aDepartment of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA 91010
bHematologic Malignancies Research Institute, City of Hope National Medical Center, Duarte, CA 91010
hCity of Hope Comprehensive Cancer Center, Duarte, CA 91010
Jianhua Yu
aDepartment of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA 91010
bHematologic Malignancies Research Institute, City of Hope National Medical Center, Duarte, CA 91010
hCity of Hope Comprehensive Cancer Center, Duarte, CA 91010
Article usage
Posted May 09, 2021.
The K18-hACE2 Transgenic Mouse Model Recapitulates Non-Severe and Severe COVID-19 in Response to Infectious Dose of SARS-CoV-2 Virus
Wenjuan Dong, Heather Mead, Sierra Jaramillo, Tasha Barr, Daniel S. Kollath, Vanessa K. Coyne, Nathan E. Stone, Ashley Jones, Jianying Zhang, Aimin Li, Li-Shu Wang, Martha Milanes-Yearsley, Paul S Keim, Bridget Marie Barker, Michael Caligiuri, Jianhua Yu
bioRxiv 2021.05.08.443244; doi: https://doi.org/10.1101/2021.05.08.443244
The K18-hACE2 Transgenic Mouse Model Recapitulates Non-Severe and Severe COVID-19 in Response to Infectious Dose of SARS-CoV-2 Virus
Wenjuan Dong, Heather Mead, Sierra Jaramillo, Tasha Barr, Daniel S. Kollath, Vanessa K. Coyne, Nathan E. Stone, Ashley Jones, Jianying Zhang, Aimin Li, Li-Shu Wang, Martha Milanes-Yearsley, Paul S Keim, Bridget Marie Barker, Michael Caligiuri, Jianhua Yu
bioRxiv 2021.05.08.443244; doi: https://doi.org/10.1101/2021.05.08.443244
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