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Cancer patient survival can be accurately parameterized, revealing time-dependent therapeutic effects and doubling the precision of small trials

View ORCID ProfileDeborah Plana, Geoffrey Fell, Brian M. Alexander, View ORCID ProfileAdam C. Palmer, View ORCID ProfilePeter K. Sorger
doi: https://doi.org/10.1101/2021.05.14.442837
Deborah Plana
1Laboratory of Systems Pharmacology and the Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
2Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School and MIT, Cambridge, Massachusetts, USA
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  • ORCID record for Deborah Plana
Geoffrey Fell
3Dana-Farber Cancer Institute, Boston, Massachusetts, USA
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Brian M. Alexander
3Dana-Farber Cancer Institute, Boston, Massachusetts, USA
4Foundation Medicine Inc., Cambridge, Massachusetts, USA
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Adam C. Palmer
5Department of Pharmacology, Computational Medicine Program, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
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  • For correspondence: palmer@unc.edu peter_sorger@hms.harvard.edu sorger_admin@hms.harvard.edu
Peter K. Sorger
1Laboratory of Systems Pharmacology and the Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
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  • For correspondence: palmer@unc.edu peter_sorger@hms.harvard.edu sorger_admin@hms.harvard.edu
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Posted May 17, 2021.
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Cancer patient survival can be accurately parameterized, revealing time-dependent therapeutic effects and doubling the precision of small trials
Deborah Plana, Geoffrey Fell, Brian M. Alexander, Adam C. Palmer, Peter K. Sorger
bioRxiv 2021.05.14.442837; doi: https://doi.org/10.1101/2021.05.14.442837
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Cancer patient survival can be accurately parameterized, revealing time-dependent therapeutic effects and doubling the precision of small trials
Deborah Plana, Geoffrey Fell, Brian M. Alexander, Adam C. Palmer, Peter K. Sorger
bioRxiv 2021.05.14.442837; doi: https://doi.org/10.1101/2021.05.14.442837

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