New Results
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication
View ORCID ProfileNatacha S. Ogando, Priscila El Kazzi, Jessika C. Zevenhoven-Dobbe, Brenda W. Bontes, Alice Decombe, Clara C. Posthuma, Volker Thiel, View ORCID ProfileBruno Canard, François Ferron, Etienne Decroly, Eric J. Snijder
doi: https://doi.org/10.1101/2021.05.17.444407
Natacha S. Ogando
1Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands, 2333ZA
Priscila El Kazzi
2Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Aix-Marseille Université, Marseille, France, 13288
Jessika C. Zevenhoven-Dobbe
1Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands, 2333ZA
Brenda W. Bontes
1Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands, 2333ZA
Alice Decombe
2Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Aix-Marseille Université, Marseille, France, 13288
Clara C. Posthuma
1Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands, 2333ZA
Volker Thiel
3European Virus Bioinformatics Center, Jena, Germany, 07743
4Institute of Virology and Immunology (IVI), Bern, Switzerland,3350
Bruno Canard
2Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Aix-Marseille Université, Marseille, France, 13288
François Ferron
2Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Aix-Marseille Université, Marseille, France, 13288
3European Virus Bioinformatics Center, Jena, Germany, 07743
Etienne Decroly
2Architecture et Fonction des Macromolécules Biologiques, Centre National de la Recherche Scientifique, Aix-Marseille Université, Marseille, France, 13288
Eric J. Snijder
1Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands, 2333ZA
Article usage
Posted November 01, 2021.
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication
Natacha S. Ogando, Priscila El Kazzi, Jessika C. Zevenhoven-Dobbe, Brenda W. Bontes, Alice Decombe, Clara C. Posthuma, Volker Thiel, Bruno Canard, François Ferron, Etienne Decroly, Eric J. Snijder
bioRxiv 2021.05.17.444407; doi: https://doi.org/10.1101/2021.05.17.444407
Structure-function analysis of the nsp14 N7-guanine methyltransferase reveals an essential role in Betacoronavirus replication
Natacha S. Ogando, Priscila El Kazzi, Jessika C. Zevenhoven-Dobbe, Brenda W. Bontes, Alice Decombe, Clara C. Posthuma, Volker Thiel, Bruno Canard, François Ferron, Etienne Decroly, Eric J. Snijder
bioRxiv 2021.05.17.444407; doi: https://doi.org/10.1101/2021.05.17.444407
Subject Area
Subject Areas
- Biochemistry (11752)
- Bioengineering (8752)
- Bioinformatics (29200)
- Biophysics (14974)
- Cancer Biology (12096)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18308)
- Genetics (12245)
- Genomics (16803)
- Immunology (11869)
- Microbiology (28097)
- Molecular Biology (11594)
- Neuroscience (60969)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)